Bis(4-aminocyclohexyl)methane

Modify Date: 2025-08-20 19:57:29

Bis(4-aminocyclohexyl)methane Structure
Bis(4-aminocyclohexyl)methane structure
Common Name Bis(4-aminocyclohexyl)methane
CAS Number 1761-71-3 Molecular Weight 210.359
Density 0.9±0.1 g/cm3 Boiling Point 320.0±0.0 °C at 760 mmHg
Molecular Formula C13H26N2 Melting Point 60-65°C
MSDS Chinese USA Flash Point 144.8±17.9 °C
Symbol GHS05 GHS07 GHS08 GHS09
GHS05, GHS07, GHS08, GHS09
Signal Word Danger

 Names

Name 4,4'-Diaminodicyclohexyl methane
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 320.0±0.0 °C at 760 mmHg
Melting Point 60-65°C
Molecular Formula C13H26N2
Molecular Weight 210.359
Flash Point 144.8±17.9 °C
Exact Mass 210.209595
PSA 52.04000
LogP 2.49
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.499
Water Solubility Insoluble (

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GX1530000
CHEMICAL NAME :
Cyclohexylamine, 4,4'-methylenebis-
CAS REGISTRY NUMBER :
1761-71-3
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C13-H26-N2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
670 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571204
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,481,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
20175 mg/kg/1.5Y-I
TOXIC EFFECTS :
Gastrointestinal - changes in structure or function of salivary glands Liver - fatty liver degeneration Kidney, Ureter, Bladder - interstitial nephritis
REFERENCE :
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 11,367,1991

 Safety Information

Symbol GHS05 GHS07 GHS08 GHS09
GHS05, GHS07, GHS08, GHS09
Signal Word Danger
Hazard Statements H302-H314-H317-H373-H411
Precautionary Statements P273-P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes T+:Verytoxic;N:Dangerous for the environment;
Risk Phrases R26;R34;R51/53
Safety Phrases S26-S28-S36/37/39-S45-S61
RIDADR UN 2928 6.1/PG 2
WGK Germany 2
RTECS GX1530000
Packaging Group III
Hazard Class 8
HS Code 2921300090

 Synthetic Route

~75%

Bis(4-aminocyclohexyl)methane Structure

Bis(4-aminocycl...

CAS#:1761-71-3

Literature: Ding, Hao; Vedage, Gamini Ananda; Martine, William R.; Dholakia, Vipul P. Patent: US2005/261525 A1, 2005 ; Location in patent: Page/Page column 4 ;

~%

Bis(4-aminocyclohexyl)methane Structure

Bis(4-aminocycl...

CAS#:1761-71-3

Literature: EP1767520 A1, ; Page/Page column 11 ;

 Preparation

1761-71-3 preparation

 Customs

HS Code 2921300090
Summary 2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles2

More Articles
Allergic contact dermatitis from dicyclohexylmethane-4,4'-diisocyanate.

Contact Dermatitis 48(6) , 305-9, (2003)

From August 1999 to April 2001, there was an outbreak of severe eczema at a factory manufacturing medical equipment. A glue, mainly based on the isocyanate dicyclohexylmethane-4,4'-diisocyanate (DMDI)...

Toxicity of 1,4-bis(aminocyclohexyl)methane.

J. Appl. Toxicol. 11(5) , 367-71, (1991)

1,4-Bis(aminocyclohexyl)methane (PACM; CAS No. 1761-71-3) is a white solid considered for use in polymeric systems. PACM is moderately toxic systemically, with the acute oral lethal dose in rats betwe...

 Synonyms

4,4-Methylenebiscyclohexylamine
hlr4448
4,4'-methanediyldicyclohexanamine
bis(para-amino-cyclohexyl)methane
Cyclohexanamine, 4,4'-methylenebis-
EINECS 217-168-8
Bis(4-aminocyclohexyl)methane
Wondamine HM
p-aminodicyclohexylmethane
DICYKAN
HLR 4219
4,4'-Methylenebis(aminocyclohexane)
4,4'-Methylenedicyclohexanamine
TRANS,TRANS-4,4'-METHYLENEBIS(CYCLOHEXYLAMINE)
4,4'-Methylenebis(cyclohexylaMine)
4,4'-Diaminodicyclohexylmethane
4,4'-methylene bis(cyclohexylamine)
4-((4-aminocyclohexyl)methyl)cyclohexanamine
Bis-(p-aminocyclohexyl)methane
MFCD00001496
di(4-aminocyclohexyl)-methane
4,4-Methylenebis(Cyclohexylamine)
bis-(4-amino cyclohexyl)-methane
PACM20
wandaminhm
Amicure PACM
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