N-(3-Methylbutyl)adenosine

Modify Date: 2024-01-02 21:19:59

N-(3-Methylbutyl)adenosine Structure
N-(3-Methylbutyl)adenosine structure
Common Name N-(3-Methylbutyl)adenosine
CAS Number 17659-78-8 Molecular Weight 337.37
Density 1.57 Boiling Point 632.9ºC at 760mmHg
Molecular Formula C15H23N5O4 Melting Point N/A
MSDS N/A Flash Point 336.5ºC

 Use of N-(3-Methylbutyl)adenosine


N-(3-Methylbutyl)adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

 Names

Name N-isopentyladenosine
Synonym More Synonyms

 N-(3-Methylbutyl)adenosine Biological Activity

Description N-(3-Methylbutyl)adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

[2]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

 Chemical & Physical Properties

Density 1.57
Boiling Point 632.9ºC at 760mmHg
Molecular Formula C15H23N5O4
Molecular Weight 337.37
Flash Point 336.5ºC
Exact Mass 337.17500
PSA 125.55000
Vapour Pressure 6.93E-17mmHg at 25°C
Index of Refraction 1.708

 Synthetic Route

~80%

N-(3-Methylbutyl)adenosine Structure

N-(3-Methylbuty...

CAS#:17659-78-8

Literature: Ottria, Roberta; Casati, Silvana; Baldoli, Erika; Maier, Jeanette A.M.; Ciuffreda, Pierangela Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 23 p. 8396 - 8402

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N-(3-Methylbutyl)adenosine Structure

N-(3-Methylbuty...

CAS#:17659-78-8

Literature: Anglin, Justin L.; Deng, Lisheng; Yao, Yuan; Cai, Guobin; Liu, Zhen; Jiang, Hong; Cheng, Gang; Chen, Pinhong; Song, Yongcheng; Dong, Shuo Journal of Medicinal Chemistry, 2012 , vol. 55, # 18 p. 8066 - 8074,9

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N-(3-Methylbutyl)adenosine Structure

N-(3-Methylbuty...

CAS#:17659-78-8

Literature: Anglin, Justin L.; Deng, Lisheng; Yao, Yuan; Cai, Guobin; Liu, Zhen; Jiang, Hong; Cheng, Gang; Chen, Pinhong; Song, Yongcheng; Dong, Shuo Journal of Medicinal Chemistry, 2012 , vol. 55, # 18 p. 8066 - 8074,9

~%

N-(3-Methylbutyl)adenosine Structure

N-(3-Methylbuty...

CAS#:17659-78-8

Literature: Anglin, Justin L.; Deng, Lisheng; Yao, Yuan; Cai, Guobin; Liu, Zhen; Jiang, Hong; Cheng, Gang; Chen, Pinhong; Song, Yongcheng; Dong, Shuo Journal of Medicinal Chemistry, 2012 , vol. 55, # 18 p. 8066 - 8074,9

 Synonyms

N6-Isopentyladenosine
Adenosine,N-(3-methylbutyl)
N-(3-Methylbutyl)adenosine
N6-(3-methyl-butyl)-adenosine