Cyprodinil-d5

Modify Date: 2024-01-28 12:08:46

Cyprodinil-d5 Structure
Cyprodinil-d5 structure
Common Name Cyprodinil-d5
CAS Number 1773496-67-5 Molecular Weight 230.32
Density N/A Boiling Point N/A
Molecular Formula C14H10D5N3 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

 Use of Cyprodinil-d5


Cyprodinil-d5is the deuterium labeledCyprodinil(HY-116214)[1]. Cyprodinil is an anilinopyrimidine broad-spectrum fungicide that inhibits the biosynthesis of methionine in phytopathogenic fungi. Cyprodinil inhibits mycelial cell growth of B. cinerea, P. herpotrichoides, and H. oryzae on amino acid-free media (IC50s=0.44, 4.8, and 0.03 μM, respectively). Cyprodinil acts as an androgen receptor (AR) agonist (EC50=1.91 μM) in the absence of the AR agonist DHT and inhibits the androgenic effect of DHT (IC50=15.1 μM)[2].

 Names

Name Cyprodinil-d5

 Cyprodinil-d5 Biological Activity

Description Cyprodinil-d5is the deuterium labeledCyprodinil(HY-116214)[1]. Cyprodinil is an anilinopyrimidine broad-spectrum fungicide that inhibits the biosynthesis of methionine in phytopathogenic fungi. Cyprodinil inhibits mycelial cell growth of B. cinerea, P. herpotrichoides, and H. oryzae on amino acid-free media (IC50s=0.44, 4.8, and 0.03 μM, respectively). Cyprodinil acts as an androgen receptor (AR) agonist (EC50=1.91 μM) in the absence of the AR agonist DHT and inhibits the androgenic effect of DHT (IC50=15.1 μM)[2].
Related Catalog
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Molecular Formula C14H10D5N3
Molecular Weight 230.32

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H315-H317-H319-H410
Precautionary Statements P273-P280-P333 + P313-P337 + P313-P391-P501
RIDADR UN 3077 9 / PGIII