(-)-Hardwickic acid

Modify Date: 2025-08-27 16:34:51

(-)-Hardwickic acid structure	Common Name	(-)-Hardwickic acid
	CAS Number	1782-65-6	Molecular Weight	316.435
	Density	1.1±0.1 g/cm3	Boiling Point	427.2±18.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₈O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	212.2±21.2 °C

Use of (-)-Hardwickic acid

Hardwickiic acid ((-)-Hardwikiic acid) is an antinociceptive compound that blocks Tetrodotoxin-sensitive voltage-dependent sodium channels. Hardwickiic acid shows insecticidal activity[1][2].

Name	(4aR,5R,6R,8aR)-5-[2-(furan-3-yl)ethyl]-5,6,8a-trimethyl-3,4,4a,6,7,8-hexahydronaphthalene-1-carboxylic acid
Synonym	More Synonyms

Description	Hardwickiic acid ((-)-Hardwikiic acid) is an antinociceptive compound that blocks Tetrodotoxin-sensitive voltage-dependent sodium channels. Hardwickiic acid shows insecticidal activity[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Infection Research Areas >> Neurological Disease
References	[1]. Cai S, et al. (-)-Hardwickiic Acid and Hautriwaic Acid Induce Antinociception via Blockade of Tetrodotoxin-Sensitive Voltage-Dependent Sodium Channels. ACS Chem Neurosci. 2019 Mar 20;10(3):1716-1728. [2]. Bandara BM, et al. Isolation and Insecticidal Activity of (-)-Hardwickiic Acid from Croton aromaticus. Planta Med. 1987 Dec;53(6):575.

Description

Hardwickiic acid ((-)-Hardwikiic acid) is an antinociceptive compound that blocks Tetrodotoxin-sensitive voltage-dependent sodium channels. Hardwickiic acid shows insecticidal activity[1][2].

Related Catalog

Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel

Research Areas >> Infection

Research Areas >> Neurological Disease

References

[1]. Cai S, et al. (-)-Hardwickiic Acid and Hautriwaic Acid Induce Antinociception via Blockade of Tetrodotoxin-Sensitive Voltage-Dependent Sodium Channels. ACS Chem Neurosci. 2019 Mar 20;10(3):1716-1728.

[2]. Bandara BM, et al. Isolation and Insecticidal Activity of (-)-Hardwickiic Acid from Croton aromaticus. Planta Med. 1987 Dec;53(6):575.

Density	1.1±0.1 g/cm3
Boiling Point	427.2±18.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₈O₃
Molecular Weight	316.435
Flash Point	212.2±21.2 °C
Exact Mass	316.203857
PSA	50.44000
LogP	6.56
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.519

Hazard Codes	Xi

1-Naphthalenecarboxylic acid, 5-[2-(3-furanyl)ethyl]-3,4,4a,5,6,7,8,8a-octahydro-5,6,8a-trimethyl-, (4aR,5S,6R,8aR)-

(-)-Hardwickiic acid

(4aR,5S,6R,8aR)-5-[2-(3-Furyl)ethyl]-5,6,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahydro-1-naphthalenecarboxylic acid

(-)-Hardwickic acid

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (-)-Hardwickic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: (-)-Hardwickic acid
Price: ￥4000.0/5mg
Purity: 98.0%
Delivery: 3 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Hardwickiic acid
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Hardwickiic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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(-)-Hardwickic acid

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