Methyl 2-isocyanatobenzoate

Modify Date: 2024-01-13 05:02:22

Methyl 2-isocyanatobenzoate Structure
Methyl 2-isocyanatobenzoate structure
Common Name Methyl 2-isocyanatobenzoate
CAS Number 1793-07-3 Molecular Weight 177.157
Density 1.2±0.1 g/cm3 Boiling Point 267.1±23.0 °C at 760 mmHg
Molecular Formula C9H7NO3 Melting Point 45-49ºC
MSDS Chinese USA Flash Point 124.8±17.1 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name Methyl 2-isocyanatobenzoate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 267.1±23.0 °C at 760 mmHg
Melting Point 45-49ºC
Molecular Formula C9H7NO3
Molecular Weight 177.157
Flash Point 124.8±17.1 °C
Exact Mass 177.042587
PSA 55.73000
LogP 3.37
Appearance of Characters Solid or Crystalline Solid | White to off-white
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.529
Storage condition 2-8℃
Water Solubility Hydrolyzes in water.

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H315-H319-H332-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;Xi: Irritant;
Risk Phrases R20/22;R36/37/38;R42
Safety Phrases S22-S26-S36/37/39-S45
RIDADR UN 2811
WGK Germany 3
Packaging Group III
Hazard Class 6.1
HS Code 2929109000

 Synthetic Route

~99%

Methyl 2-isocyanatobenzoate Structure

Methyl 2-isocya...

CAS#:1793-07-3

Literature: SPIROGEN LIMITED Patent: WO2005/23814 A1, 2005 ; Location in patent: Page/Page column 106 ;

~%

Methyl 2-isocyanatobenzoate Structure

Methyl 2-isocya...

CAS#:1793-07-3

Literature: Journal of Medicinal Chemistry, , vol. 33, # 7 p. 1932 - 1935

~%

Methyl 2-isocyanatobenzoate Structure

Methyl 2-isocya...

CAS#:1793-07-3

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 24 p. 6723 - 6728

~%

Methyl 2-isocyanatobenzoate Structure

Methyl 2-isocya...

CAS#:1793-07-3

Literature: Heterocycles, , vol. 36, # 6 p. 1305 - 1314

~%

Methyl 2-isocyanatobenzoate Structure

Methyl 2-isocya...

CAS#:1793-07-3

Literature: Russian Journal of General Chemistry, , vol. 76, # 7 p. 1069 - 1080

 Customs

HS Code 2929109000
Summary 2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles4

More Articles
Explorations of substituted urea functionality for the discovery of new activators of the heme-regulated inhibitor kinase.

J. Med. Chem. 56(23) , 9457-70, (2013)

Heme-regulated inhibitor kinase (HRI), a eukaryotic translation initiation factor 2 alpha (eIF2α) kinase, plays critical roles in cell proliferation, differentiation, and adaptation to cytoplasmic str...

Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivo.

J. Biol. Chem. 284 , 7673-7680, (2009)

Retinol-binding protein 4 (RBP4) transports retinol from the liver to extrahepatic tissues, and RBP4 lowering is reported to improve insulin sensitivity in mice. We have identified A1120, a high affin...

ortho-Lithiophenyl isocyanide: a versatile precursor for 3H-quinazolin-4-ones and 3H-quinazolin-4-thiones.

Org. Lett. 11(2) , 389-92, (2009)

ortho-Lithiophenyl isocyanide has been generated from ortho-bromophenyl isocyanide and successfully employed toward the synthesis of 2-substituted phenyl isocyanides as well as 2,3-disubstituted 3H-qu...

 Synonyms

MFCD00013848
2-isocyanato-benzoic acid methyl ester
methyl 2-(isocyanato)benzoate
2-Methoxycarbonylphenyl isocyanate
Benzoic acid, 2-isocyanato-, methyl ester
2-(METHOXYCARBONYL)PHENYL ISOCYANATE
2-Carbomethoxyphenyl isocyanate
Methyl 2-isocyanatobenzoate