PD150606
Modify Date: 2025-08-23 09:23:07
PD150606 structure
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Common Name | PD150606 | ||
|---|---|---|---|---|
| CAS Number | 179528-45-1 | Molecular Weight | 306.120 | |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 410.4±45.0 °C at 760 mmHg | |
| Molecular Formula | C9H7IO2S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 202.0±28.7 °C | |
| Symbol |
GHS05, GHS06 |
Signal Word | Danger | |
Use of PD150606PD 150606 is a selective, cell-permeable non-peptide calpain inhibitor (Ki values for ν and m-calpains are 0.21 and 0.37 μM respectively).target:calpain[1]In vitro: PD150606 also against tetrafluoroethyl-l-cysteine-, bromohydroquinone-, oxidant (t-butylhydroperoxide)- and calcium ionophore (ionomycin)-induced cell death. PD150606 inhibits calpains by binding to the calcium-binding domain of the enzyme. [2] high specificity for calpains relative to other proteases, uncompetitive inhibition with respect to substrate.[3] |
| Name | (Z)-3-(4-iodophenyl)-2-sulfanylprop-2-enoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | PD 150606 is a selective, cell-permeable non-peptide calpain inhibitor (Ki values for ν and m-calpains are 0.21 and 0.37 μM respectively).target:calpain[1]In vitro: PD150606 also against tetrafluoroethyl-l-cysteine-, bromohydroquinone-, oxidant (t-butylhydroperoxide)- and calcium ionophore (ionomycin)-induced cell death. PD150606 inhibits calpains by binding to the calcium-binding domain of the enzyme. [2] high specificity for calpains relative to other proteases, uncompetitive inhibition with respect to substrate.[3] |
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| Related Catalog | |
| References |
| Density | 1.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 410.4±45.0 °C at 760 mmHg |
| Molecular Formula | C9H7IO2S |
| Molecular Weight | 306.120 |
| Flash Point | 202.0±28.7 °C |
| Exact Mass | 305.921143 |
| PSA | 76.10000 |
| LogP | 4.25 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.732 |
| InChIKey | DJCVSFWGKYHMKH-YVMONPNESA-N |
| SMILES | O=C(O)C(S)=Cc1ccc(I)cc1 |
| Storage condition | 2-8℃ |
| Symbol |
GHS05, GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H315-H317-H318-H335 |
| Precautionary Statements | P261-P280-P301 + P310-P305 + P351 + P338 |
| RIDADR | UN 2811 6.1 / PGIII |
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Improved performance of aminopropylsilatrane over aminopropyltriethoxysilane as an adhesive film for anchoring gold nanoparticles on silicon surfaces.
J. Nanosci. Nanotechnol. 9 , 2894-901, (2009) Aminopropylsilatrane (AP-silatrane) was investigated as an adhesive layer for anchoring Au nanoparticles on silicon substrates. We compared the preparation procedure and film quality of the AP-silatra... |
| (Z)-3-(4-iodophenyl)-2-mercaptoacrylic acid |
| PD150606 |
| (2Z)-3-(4-Iodophenyl)-2-sulfanylacrylic acid |
| (2Z)-3-(4-iodophenyl)-2-sulfanylprop-2-enoic acid |
| 2-Propenoic acid, 3-(4-iodophenyl)-2-mercapto-, (2Z)- |