BMS-986163

Modify Date: 2025-08-22 10:59:24

BMS-986163 Structure
BMS-986163 structure
Common Name BMS-986163
CAS Number 1801151-09-6 Molecular Weight 462.45
Density N/A Boiling Point N/A
Molecular Formula C23H28FN2O5P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BMS-986163


BMS-986163 is a negative allosteric modulator of GluN2B. The prodrug BMS-986163 rapidly converts to its active parent molecule BMS-986169 (Ki=4 nM, IC50=24 nM).

 Names

Name BMS-986163

 BMS-986163 Biological Activity

Description BMS-986163 is a negative allosteric modulator of GluN2B. The prodrug BMS-986163 rapidly converts to its active parent molecule BMS-986169 (Ki=4 nM, IC50=24 nM).
Related Catalog
Target

IC50: 4 nM (GluN2B, BMS-986169), 24 nM (GluN2B, BMS-986169)[1]

References

[1]. Marcin LR, et al. BMS-986163, a Negative Allosteric Modulator of GluN2B with Potential Utility in Major Depressive Disorder. ACS Med Chem Lett. 2018 Apr 13;9(5):472-477.

 Chemical & Physical Properties

Molecular Formula C23H28FN2O5P
Molecular Weight 462.45
InChIKey ZPUVTBAQHJFPHE-BHDDXSALSA-N
SMILES Cc1ccc(CN2CCC(N3CCC(c4ccc(OP(=O)(O)O)cc4)C(F)C3)C2=O)cc1
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here



Get all suppliers and price by the below link:

BMS-986163 suppliers

BMS-986163 price