Ph-Bis(C1-N-(C2-NH-Boc)2)

Modify Date: 2024-01-06 15:30:29

Ph-Bis(C1-N-(C2-NH-Boc)2) Structure
Ph-Bis(C1-N-(C2-NH-Boc)2) structure
Common Name Ph-Bis(C1-N-(C2-NH-Boc)2)
CAS Number 1807521-06-7 Molecular Weight 708.93
Density N/A Boiling Point N/A
Molecular Formula C36H64N6O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ph-Bis(C1-N-(C2-NH-Boc)2)


Ph-Bis(C1-N-(C2-NH-Boc)2) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Ph-Bis(C1-N-(C2-NH-Boc)2)
Synonym More Synonyms

 Ph-Bis(C1-N-(C2-NH-Boc)2) Biological Activity

Description Ph-Bis(C1-N-(C2-NH-Boc)2) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C36H64N6O8
Molecular Weight 708.93

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD28142457