Ubiquitination-IN-1
Modify Date: 2024-01-16 18:07:26
Ubiquitination-IN-1 structure
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Common Name | Ubiquitination-IN-1 | ||
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| CAS Number | 1819330-15-8 | Molecular Weight | 429.41 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H14F3N3O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ubiquitination-IN-1Ubiquitination-IN-1 (compound 24) is a ubiquitination and Cksl-Skp2 protein-protein interaction (IC50=0.17 μM) inhibitor. Ubiquitination-IN-1 increases levels of p27. Ubiquitination-IN-1 can be used to treat disease by blocking the degradation of tumor suppressors[1]. |
| Name | Ubiquitination-IN-1 |
|---|
| Description | Ubiquitination-IN-1 (compound 24) is a ubiquitination and Cksl-Skp2 protein-protein interaction (IC50=0.17 μM) inhibitor. Ubiquitination-IN-1 increases levels of p27. Ubiquitination-IN-1 can be used to treat disease by blocking the degradation of tumor suppressors[1]. |
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| Related Catalog | |
| In Vitro | Ubiquitination-IN-1 inhibits A549 and HT1080 cells with IC50s of 0.91 and 0.4 μM, respectively[1]. |
| References |
[1]. David Carroll, et al.Quinoline derivatives useful as ubiquitination inhibitors. WO2016025779A1. |
| Molecular Formula | C21H14F3N3O2S |
|---|---|
| Molecular Weight | 429.41 |