![]() HIV-1 inhibitor-6 structure
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Common Name | HIV-1 inhibitor-6 | ||
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CAS Number | 1821309-39-0 | Molecular Weight | 330.32 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C14H10N4O4S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of HIV-1 inhibitor-6HIV-1 inhibitor-6 (compound 9), a diheteroarylamide-based compound, is a potent HIV-1 pre-mRNA alternative splicing inhibitor. HIV-1 inhibitor-6 blocks HIV replication. HIV-1 inhibitor-6 is active against wild-type HIV-1IIIB (subtype B, X4-tropic) and HIV-1 97USSN54 (subtype A, R5-tropic) with EC50s of 0.6 μM and 0.9 μM, respectively. HIV-1 inhibitor-6 inhibits HIV strains resistant to drugs targeting HIV reverse transcriptase, protease, integrase, and coreceptor CCR5 with EC50s ranging from 0.9 to 1.5 μM[1]. |
Name | HIV-1 inhibitor-6 |
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Description | HIV-1 inhibitor-6 (compound 9), a diheteroarylamide-based compound, is a potent HIV-1 pre-mRNA alternative splicing inhibitor. HIV-1 inhibitor-6 blocks HIV replication. HIV-1 inhibitor-6 is active against wild-type HIV-1IIIB (subtype B, X4-tropic) and HIV-1 97USSN54 (subtype A, R5-tropic) with EC50s of 0.6 μM and 0.9 μM, respectively. HIV-1 inhibitor-6 inhibits HIV strains resistant to drugs targeting HIV reverse transcriptase, protease, integrase, and coreceptor CCR5 with EC50s ranging from 0.9 to 1.5 μM[1]. |
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Related Catalog | |
Target |
X4 HIV-1 (IIIB):0.6 μM (EC50) R5 HIV-1:0.9 μM (EC50) |
References |
Molecular Formula | C14H10N4O4S |
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Molecular Weight | 330.32 |