POL1-IN-1
Modify Date: 2025-08-27 13:02:01
POL1-IN-1 structure
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Common Name | POL1-IN-1 | ||
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| CAS Number | 1822358-25-7 | Molecular Weight | 356.42400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H20N6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of POL1-IN-1POL1-IN-1 is a RNA polymerase 1 (POL1, also known as Pol I) inhibitor with an IC50 of less than 0.5 uM. POL1-IN-1 inhibits ribosome biogenesis by inhibiting POL1 transcription[1]. |
| Name | 2-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzo[4,5]imidazo[1,2-a][1,8]naphthyridine-6-carbonitrile |
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| Description | POL1-IN-1 is a RNA polymerase 1 (POL1, also known as Pol I) inhibitor with an IC50 of less than 0.5 uM. POL1-IN-1 inhibits ribosome biogenesis by inhibiting POL1 transcription[1]. |
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| Related Catalog | |
| References |
[1]. Mustapha Haddach. Compositions, uses and methods for making them. US9758518B2. |
| Molecular Formula | C21H20N6 |
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| Molecular Weight | 356.42400 |
| Exact Mass | 356.17500 |
| PSA | 69.25000 |
| LogP | 3.48778 |
| Storage condition | -20°C |
| Hazard Codes | Xn |
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