Taxinine B

Modify Date: 2024-01-09 17:55:32

Taxinine B structure	Common Name	Taxinine B
	CAS Number	18457-44-8	Molecular Weight	664.74
	Density	1.2±0.1 g/cm3	Boiling Point	705.4±60.0 °C at 760 mmHg
	Molecular Formula	C₃₇H₄₄O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	286.7±32.9 °C

Use of Taxinine B

Taxinine B is a taxoid that can be isolated from Japanese Yew Taxus Cuspid. Taxinine B inhibits CaCl2-induced depolymerization of microtubule. Taxinine B is useful for overcoming multidrug resistance in tumor cells[1].

Name	Taxinine B
Synonym	More Synonyms

Description	Taxinine B is a taxoid that can be isolated from Japanese Yew Taxus Cuspid. Taxinine B inhibits CaCl2-induced depolymerization of microtubule. Taxinine B is useful for overcoming multidrug resistance in tumor cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Juníchi Kobayashi, et al. Taxuspines A ∼ C, new taxoids from Japanese yew Taxus cuspidata inhibiting drug transport activity of P-glycoprotein in multidrug-resistant cells. Tetrahedron. 1994. 50 (25), 7401-7416.

Density	1.2±0.1 g/cm3
Boiling Point	705.4±60.0 °C at 760 mmHg
Molecular Formula	C₃₇H₄₄O₁₁
Molecular Weight	664.74
Flash Point	286.7±32.9 °C
Exact Mass	664.288391
PSA	148.57000
LogP	5.60
Vapour Pressure	0.0±2.2 mmHg at 25°C
Index of Refraction	1.558

Hazard Codes	Xi

2-Propenoic acid, 3-phenyl-, (1S,3S,4aR,5R,6R,11R,12R,12aS)-1,5,11,12-tetrakis(acetyloxy)-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-9,12a,13,13-tetramethyl-4-methylene-8-oxo-6,10-methanobenzocyclodecen-3-yl ester, (2E)-

(2α,5α,7β,9α,10β)-2,7,9,10-tetrakis(acetyloxy)-13-oxotaxa-4(20),11-dien-5-yl (2E)-3-phenylprop-2-enoate

(2α,5α,7β,9α,10β)-2,7,9,10-Tetraacetoxy-13-oxotaxa-4(20),11-dien-5-yl (2E)-3-phenylacrylate