2-(4-(2-Amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide

Modify Date: 2023-10-16 18:10:56

2-(4-(2-Amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide Structure
2-(4-(2-Amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide structure
Common Name 2-(4-(2-Amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide
CAS Number 185298-58-2 Molecular Weight 379.41
Density 1.3±0.1 g/cm3 Boiling Point 709.0±70.0 °C at 760 mmHg
Molecular Formula C21H21N3O4 Melting Point N/A
MSDS N/A Flash Point 382.6±35.7 °C

 Use of 2-(4-(2-Amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide


hnps-PLA-IN-1 (compound 5aa), a indole-3-acetamide, is a hnps-PLA2 inhibitor (IC50=0.124 μM)[1].

 Names

Name 2-[4-(2-Amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl]-2-oxoacetamide
Synonym More Synonyms

  Biological Activity

Description hnps-PLA-IN-1 (compound 5aa), a indole-3-acetamide, is a hnps-PLA2 inhibitor (IC50=0.124 μM)[1].
Related Catalog
Target

IC50: 0.124 μM (hnps-PLA2)[1]

References

[1]. Draheim SE, et al. Indole inhibitors of human nonpancreatic secretory phospholipase A2. 3. Indole-3-glyoxamides. J Med Chem. 1996 Dec 20;39(26):5159-75.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 709.0±70.0 °C at 760 mmHg
Molecular Formula C21H21N3O4
Molecular Weight 379.41
Flash Point 382.6±35.7 °C
Exact Mass 379.153198
LogP 1.86
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.639
Storage condition -20℃

 Synonyms

MFCD29035152
1H-Indole-3-acetamide, 4-(2-amino-2-oxoethoxy)-2-ethyl-α-oxo-1-(phenylmethyl)-
2-[4-(2-Amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl]-2-oxoacetamide
2-(4-(2-Amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide
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Price: ¥1500/5 mg

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