WX-081

Modify Date: 2025-08-24 20:27:01

WX-081 Structure
WX-081 structure
Common Name WX-081
CAS Number 1859978-72-5 Molecular Weight 537.09
Density N/A Boiling Point N/A
Molecular Formula C34H33ClN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of WX-081


WX-081, an anti-tuberculosis agent, displays excellent anti-mycobacterial activity against M. tuberculosis H37Rv and low cytotoxicity. WX-081 exhibits potent activity with MIC50s of 0.083 and 0.11 μg/mL for drug susceptible tuberculosis (DS-TB) and multidrug resistant tuberculosis (MDR-TB) strains. WX-081 also inhibits hERG channel with the IC50 of 1.89 μM[1].

 Names

Name WX-081

 WX-081 Biological Activity

Description WX-081, an anti-tuberculosis agent, displays excellent anti-mycobacterial activity against M. tuberculosis H37Rv and low cytotoxicity. WX-081 exhibits potent activity with MIC50s of 0.083 and 0.11 μg/mL for drug susceptible tuberculosis (DS-TB) and multidrug resistant tuberculosis (MDR-TB) strains. WX-081 also inhibits hERG channel with the IC50 of 1.89 μM[1].
Related Catalog
References

[1]. Zhigang Huang, et al. Discovery and preclinical profile of sudapyridine (WX-081), a novel anti-tuberculosis agent. Bioorg Med Chem Lett. 2022 Sep 1;71:128824.

 Chemical & Physical Properties

Molecular Formula C34H33ClN2O2
Molecular Weight 537.09
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