Dacisteine

Modify Date: 2024-01-08 19:53:37

Dacisteine Structure
Dacisteine structure
Common Name Dacisteine
CAS Number 18725-37-6 Molecular Weight 205.23200
Density 1.314g/cm3 Boiling Point 446.8ºC at 760 mmHg
Molecular Formula C7H11NO4S Melting Point 114-116°C
MSDS N/A Flash Point 224ºC

 Use of Dacisteine


Dacisteine (N,S-Diacetyl-L-cysteine) is a cysteine derivative and displays a less New Delhi metallo-beta-lactamase-1 (NDM-1) inhibitor with an IC50 value of 1000 μM[1]. Dacisteine can be used for the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation[2].

 Names

Name (2R)-2-acetamido-3-acetylsulfanylpropanoic acid
Synonym More Synonyms

 Dacisteine Biological Activity

Description Dacisteine (N,S-Diacetyl-L-cysteine) is a cysteine derivative and displays a less New Delhi metallo-beta-lactamase-1 (NDM-1) inhibitor with an IC50 value of 1000 μM[1]. Dacisteine can be used for the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation[2].
Related Catalog
Target

IC50: 1000 μM (NDM-1)[1]

In Vivo Dacisteine is a preparing agent for treating or preventing cardiovascular and cerebrovascular diseases caused by platelet aggregation.
References

[1]. Cui-Gai Bai1, et al. Cysteine and Its Derivatives as New Delhi Metallo-beta-lactamase-1 Inhibitors. Current Enzyme Inhibition, 2015, 11, 46-57

[2]. FanKe, et al.Application of compound of thioether acid structure in preparing anti-platelet aggregation drugs. Patent WO2019007015A1.

 Chemical & Physical Properties

Density 1.314g/cm3
Boiling Point 446.8ºC at 760 mmHg
Melting Point 114-116°C
Molecular Formula C7H11NO4S
Molecular Weight 205.23200
Flash Point 224ºC
Exact Mass 205.04100
PSA 108.77000
LogP 0.24630
Vapour Pressure 3.13E-09mmHg at 25°C
Index of Refraction 1.522
Storage condition Refrigerator

 Safety Information

HS Code 2930909090

 Synthetic Route

~81%

Dacisteine Structure

Dacisteine

CAS#:18725-37-6

Literature: Pharmazie, , vol. 49, # 4 p. 249 - 252

~%

Dacisteine Structure

Dacisteine

CAS#:18725-37-6

Literature: Farmaco, Edizione Scientifica, , vol. 31, # 11 p. 767 - 775

~%

Dacisteine Structure

Dacisteine

CAS#:18725-37-6

Literature: Biochemical Journal, , vol. 57, p. 360,363

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles1

More Articles
Formation of the thioester, N,S-diacetylcysteine, from acetaldehyde and N,N'diacetylcystine in aqueous solution with ultraviolet light.

J. Mol. Evol. 17(2) , 103-7, (1981)

The thioester, N,S-diacetylcysteine, is formed during the illumination of phosphate buffered (pH 7.0) aqueous solutions of acetaldehyde and N,N'-diacetylcystine with ultraviolet light. The yield of N,...

 Synonyms

Dacisteina
Dacisteine
S,N-diacetylcysteine
N,S-Diacetyl
Acetylcysteine impurity D
N,S-diacetyl-D,L-cysteine
N,S-diacetyl-L-cysteine
N,S-Diacetylcysteine
Dacisteinum
N,S-diacetil-L-cisteina
Top Suppliers:I want be here




Get all suppliers and price by the below link:

Dacisteine suppliers

Dacisteine price