LXRβ agonist 17
Modify Date: 2024-09-20 12:05:12
LXRβ agonist 17 structure
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Common Name | LXRβ agonist 17 | ||
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| CAS Number | 1878259-00-7 | Molecular Weight | 488.526 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H27F3N4O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LXRβ agonist 17A novel, potent, orally active liver X receptor β (LXRβ) agonist with Ki/EC50 of 3/21 nM, displays 27-fold selectivity over LXRα; also exhibits excellent selectivity against other nuclear hormone receptors (>3,000-fold); induces the expression of LXR target genes in vitro and in vivo. |
| Name | LXRβ agonist 17 |
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| Description | A novel, potent, orally active liver X receptor β (LXRβ) agonist with Ki/EC50 of 3/21 nM, displays 27-fold selectivity over LXRα; also exhibits excellent selectivity against other nuclear hormone receptors (>3,000-fold); induces the expression of LXR target genes in vitro and in vivo. |
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| References | References 1. Zheng Y, et al. J Med Chem. 2016 Apr 14;59(7):3264-71. View Related Products by Target Liver X Receptor (LXR) |
| Molecular Formula | C21H27F3N4O4S |
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| Molecular Weight | 488.526 |