1878259-00-7

1878259-00-7 structure

Name: LXRβ agonist 17
Chemical Name: LXRβ agonist 17
CAS Number: 1878259-00-7
Molecular Formula: C₂₁H₂₇F₃N₄O₄S
Molecular Weight: 488.526
Create Date: 2020-01-12 10:18:49
Modify Date: 2023-01-11 23:56:26
A novel, potent, orally active liver X receptor β (LXRβ) agonist with Ki/EC50 of 3/21 nM, displays 27-fold selectivity over LXRα; also exhibits excellent selectivity against other nuclear hormone receptors (>3,000-fold); induces the expression of LXR target genes in vitro and in vivo.

Name	LXRβ agonist 17

Description	A novel, potent, orally active liver X receptor β (LXRβ) agonist with Ki/EC50 of 3/21 nM, displays 27-fold selectivity over LXRα; also exhibits excellent selectivity against other nuclear hormone receptors (>3,000-fold); induces the expression of LXR target genes in vitro and in vivo.
References	References 1. Zheng Y, et al. J Med Chem. 2016 Apr 14;59(7):3264-71. View Related Products by Target Liver X Receptor (LXR)

Molecular Formula	C₂₁H₂₇F₃N₄O₄S
Molecular Weight	488.526