1878259-00-7
1878259-00-7 structure
- Name: LXRβ agonist 17
- Chemical Name: LXRβ agonist 17
- CAS Number: 1878259-00-7
- Molecular Formula: C21H27F3N4O4S
- Molecular Weight: 488.526
- Create Date: 2020-01-12 10:18:49
- Modify Date: 2024-09-20 12:05:12
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A novel, potent, orally active liver X receptor β (LXRβ) agonist with Ki/EC50 of 3/21 nM, displays 27-fold selectivity over LXRα; also exhibits excellent selectivity against other nuclear hormone receptors (>3,000-fold); induces the expression of LXR target genes in vitro and in vivo.
| Name | LXRβ agonist 17 |
|---|
| Description | A novel, potent, orally active liver X receptor β (LXRβ) agonist with Ki/EC50 of 3/21 nM, displays 27-fold selectivity over LXRα; also exhibits excellent selectivity against other nuclear hormone receptors (>3,000-fold); induces the expression of LXR target genes in vitro and in vivo. |
|---|---|
| References | References 1. Zheng Y, et al. J Med Chem. 2016 Apr 14;59(7):3264-71. View Related Products by Target Liver X Receptor (LXR) |
| Molecular Formula | C21H27F3N4O4S |
|---|---|
| Molecular Weight | 488.526 |