Paederosidic acid structure
|
Common Name | Paederosidic acid | ||
---|---|---|---|---|
CAS Number | 18842-98-3 | Molecular Weight | 464.441 | |
Density | 1.7±0.1 g/cm3 | Boiling Point | 748.1±70.0 °C at 760 mmHg | |
Molecular Formula | C18H24O12S | Melting Point | N/A | |
MSDS | N/A | Flash Point | 406.2±35.7 °C |
Use of Paederosidic acidPaederosidic acid is isolated from P. scandens with anticancer and anti‐inflammation activities. Paederosidic acid inhibits lung caner cells via inducing mitochondria-mediated apoptosis[1]. |
Name | (1S,4aS,5S,7aS)-1-(β-D-Glucopyranosyloxy)-5-hydroxy-7-({[(methyls ulfanyl)carbonyl]oxy}methyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyr an-4-carboxylic acid |
---|---|
Synonym | More Synonyms |
Description | Paederosidic acid is isolated from P. scandens with anticancer and anti‐inflammation activities. Paederosidic acid inhibits lung caner cells via inducing mitochondria-mediated apoptosis[1]. |
---|---|
Related Catalog | |
Target |
IC50: apoptosis[1] |
In Vitro | Paederosidic acid (40 μg/ml; 24 hours and 48 hours) has no significant effect on BSAS-2B cells, it exhibits obvious effects on NCI-H1650, HCC827, A549 cells with IC50 values of 40.68, 42.58, and 36.48 μg/ml, respectively[1]. Paederosidic acid induces mitochondria-mediated apoptosis via up-regulation of caspase-3, caspase-8, caspase-9, Bid, Bax, down-regulation of Bcl-2 and stimulating the release of Cyto-C from mitochondria in lung cancer cells[1]. . |
References |
Density | 1.7±0.1 g/cm3 |
---|---|
Boiling Point | 748.1±70.0 °C at 760 mmHg |
Molecular Formula | C18H24O12S |
Molecular Weight | 464.441 |
Flash Point | 406.2±35.7 °C |
Exact Mass | 464.098846 |
PSA | 217.74000 |
LogP | -1.48 |
Vapour Pressure | 0.0±5.6 mmHg at 25°C |
Index of Refraction | 1.666 |
paederosidic acid |
(1S,4aS,5S,7aS)-1-(β-D-Glucopyranosyloxy)-5-hydroxy-7-({[(methylsulfanyl)carbonyl]oxy}methyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid |
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-[[[(methylthio)carbonyl]oxy]methyl]-, (1S,4aS,5S,7aS)- |