Amino-PEG3-CH2CO2-t-butyl ester

Modify Date: 2024-01-09 16:24:16

Amino-PEG3-CH2CO2-t-butyl ester Structure
Amino-PEG3-CH2CO2-t-butyl ester structure
Common Name Amino-PEG3-CH2CO2-t-butyl ester
CAS Number 189808-70-6 Molecular Weight 263.33
Density N/A Boiling Point N/A
Molecular Formula C12H25NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amino-PEG3-CH2CO2-t-butyl ester


PROTAC Linker 5 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 5 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name PROTAC Linker 5
Synonym More Synonyms

 Amino-PEG3-CH2CO2-t-butyl ester Biological Activity

Description PROTAC Linker 5 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 5 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C12H25NO5
Molecular Weight 263.33

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD30730374