Chlorthiamid

Modify Date: 2024-01-07 13:26:02

Chlorthiamid structure	Common Name	Chlorthiamid
	CAS Number	1918-13-4	Molecular Weight	206.09200
	Density	1.473g/cm3	Boiling Point	320.6ºC at 760mmHg
	Molecular Formula	C₇H₅Cl₂NS	Melting Point	151-152°C
	MSDS	Chinese USA	Flash Point	>100 °C
	Symbol	GHS07	Signal Word	Warning

Use of Chlorthiamid

Chlorthiamid is a broad-spectrum herbicide. Chlorthiamid is an olfactory toxicant with a high in vivo covalent binding in the olfactory mucosa of mice[1].

Name	chlorthiamid
Synonym	More Synonyms

Description	Chlorthiamid is a broad-spectrum herbicide. Chlorthiamid is an olfactory toxicant with a high in vivo covalent binding in the olfactory mucosa of mice[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. C Eriksson, et al. Effects of the herbicide chlorthiamid on the olfactory mucosa. Toxicol Lett. 1995 Apr;76(3):203-8.

Density	1.473g/cm3
Boiling Point	320.6ºC at 760mmHg
Melting Point	151-152°C
Molecular Formula	C₇H₅Cl₂NS
Molecular Weight	206.09200
Flash Point	>100 °C
Exact Mass	204.95200
PSA	58.11000
LogP	3.32790
Vapour Pressure	0.000314mmHg at 25°C
Index of Refraction	1.669

Chlorthiamid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV3850000

CHEMICAL NAME :: Benzamide, 2,6-dichlorothio-

CAS REGISTRY NUMBER :: 1918-13-4

LAST UPDATED :: 199712

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C7-H5-Cl2-N-S

MOLECULAR WEIGHT :: 206.09

WISWESSER LINE NOTATION :: SUYZR BG FG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 757 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Behavioral - general anesthetic

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 242 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - sleep

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Gastrointestinal - nausea or vomiting

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - domestic

DOSE/DURATION :: 125 mg/kg

TOXIC EFFECTS :: Behavioral - sleep

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 16800 mg/kg/4W-C

TOXIC EFFECTS :: Liver - changes in liver weight Blood - changes in bone marrow (not otherwise specified) Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 173 mg/kg/13W-C

TOXIC EFFECTS :: Liver - changes in liver weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3150 mg/kg/21D-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

REFERENCE :: CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- Volume(issue)/page/year: 14(6),38,1980

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	S36
RIDADR	NONH for all modes of transport
RTECS	CV3850000
HS Code	2930909056

2,6-Dichloroben...

CAS#:1194-65-6

~88%

Chlorthiamid

CAS#:1918-13-4

Literature: WO2012/35039 A1, ; Page/Page column 78 ; WO 2012/035039 A1

2,6-Dichloroben...

CAS#:25185-95-9

Chlorthiamid

CAS#:1918-13-4

Literature: Synthesis, , vol. 44, # 3 art. no. H102311SS, p. 377 - 379

Precursor 2
CAS#:1194-65-6 2,6-Dichloroben... CAS#:25185-95-9 2,6-Dichloroben...
DownStream 1
CAS#:111225-65-1 amino-(2,6-dich...

HS Code	2930909056
Summary	2930909056 2,6-dichlorobenzothioamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

Toxicity of 2,6-dichlorothiobenzamide (chlorthiamid) and 2,6-dichlorobenzamide in the olfactory nasal mucosa of mice.

Fundam. Appl. Toxicol. 17(1) , 92-102, (1991)

The toxic effects of the herbicide chlorthiamid (2,6-dichlorothiobenzamide) and its major environmental metabolite 2,6-dichlorobenzamide (DCBA) were examined in the nasal passages of C57Bl mice follow...

Metabolism of 2,6-dichlorobenzonitrile, 2,6-dichlorothiobenzamide in rodents and goats.

Xenobiotica 18(9) , 1063-75, (1988)

1. Twelve 14C-labelled metabolites were isolated from either urine or bile from either rats (11 metabolites) or goats (7 metabolites) given single oral doses of 2,6-dichlorobenzo[14C]nitrile (DCBN). F...

Effects of the herbicide chlorthiamid on the olfactory mucosa.

Toxicol. Lett. 76(3) , 203-8, (1995)

Chlorthiamid (2,6-dichlorothiobenzamide) and its major metabolite 2,6-dichlorobenzonitrile are olfactory toxicants with a high in vivo covalent binding in the olfactory mucosa of mice. This study show...

2,6-dichlorobenzothioamide

2,6-dichlorothiobenzamide

Chlorothiamide

Prefix

Chlorthioamide

MFCD00053523

2,6-dichlorobenzenecarbothioamide

2,5-DICHLOROBENZYL BROMIDE

DCBN

2,6-Dichlorobenzenecarbothioamide,2,6-Dichlorothiobenzamide

2,6 dichlorothiobenzamide

Chlorthiamide

Chlortiamid

CHLORTHIAMID

EINECS 217-637-7

DC Chemicals Limited
China
Product Name: Chlorthiamid
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,6-dichlorothiobenzamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Chlorthiamid

Use of Chlorthiamid

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Chlorthiamid Biological Activity

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