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1918-13-4

1918-13-4 structure
1918-13-4 structure

Name chlorthiamid
Synonyms 2,6-dichlorobenzothioamide
2,6-dichlorothiobenzamide
Chlorothiamide
Prefix
Chlorthioamide
MFCD00053523
2,6-dichlorobenzenecarbothioamide
2,5-DICHLOROBENZYL BROMIDE
DCBN
2,6-Dichlorobenzenecarbothioamide,2,6-Dichlorothiobenzamide
2,6 dichlorothiobenzamide
Chlorthiamide
Chlortiamid
CHLORTHIAMID
EINECS 217-637-7
Description Chlorthiamid is a broad-spectrum herbicide. Chlorthiamid is an olfactory toxicant with a high in vivo covalent binding in the olfactory mucosa of mice[1].
Related Catalog
References

[1]. C Eriksson, et al. Effects of the herbicide chlorthiamid on the olfactory mucosa. Toxicol Lett. 1995 Apr;76(3):203-8.  

Density 1.473g/cm3
Boiling Point 320.6ºC at 760mmHg
Melting Point 151-152°C
Molecular Formula C7H5Cl2NS
Molecular Weight 206.09200
Flash Point >100 °C
Exact Mass 204.95200
PSA 58.11000
LogP 3.32790
Vapour Pressure 0.000314mmHg at 25°C
Index of Refraction 1.669

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CV3850000
CHEMICAL NAME :
Benzamide, 2,6-dichlorothio-
CAS REGISTRY NUMBER :
1918-13-4
LAST UPDATED :
199712
DATA ITEMS CITED :
13
MOLECULAR FORMULA :
C7-H5-Cl2-N-S
MOLECULAR WEIGHT :
206.09
WISWESSER LINE NOTATION :
SUYZR BG FG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
757 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
242 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Behavioral - sleep
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Gastrointestinal - nausea or vomiting
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Behavioral - sleep
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
16800 mg/kg/4W-C
TOXIC EFFECTS :
Liver - changes in liver weight Blood - changes in bone marrow (not otherwise specified) Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
173 mg/kg/13W-C
TOXIC EFFECTS :
Liver - changes in liver weight
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3150 mg/kg/21D-I
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
REFERENCE :
CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- Volume(issue)/page/year: 14(6),38,1980
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases S36
RIDADR NONH for all modes of transport
RTECS CV3850000
HS Code 2930909056

~88%

1918-13-4 structure

1918-13-4

Literature: WO2012/35039 A1, ; Page/Page column 78 ; WO 2012/035039 A1

~%

1918-13-4 structure

1918-13-4

Literature: Synthesis, , vol. 44, # 3 art. no. H102311SS, p. 377 - 379
Precursor  2

DownStream  1

HS Code 2930909056
Summary 2930909056 2,6-dichlorobenzothioamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%