CFTR corrector 8

Modify Date: 2025-08-24 22:35:58

CFTR corrector 8 Structure
CFTR corrector 8 structure
Common Name CFTR corrector 8
CAS Number 1918142-35-4 Molecular Weight 539.52
Density N/A Boiling Point N/A
Molecular Formula C29H27F2NO7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CFTR corrector 8


CFTR corrector 8 is a potent CFTR modulator. CFTR can be used in the research of cystic fibrosis[1].

 Names

Name CFTR corrector 8

 CFTR corrector 8 Biological Activity

Description CFTR corrector 8 is a potent CFTR modulator. CFTR can be used in the research of cystic fibrosis[1].
Related Catalog
In Vitro CFTR corrector 8 (compound 12) shows EC50s of 1 μM (CSE-HRP assay) and 3 μM (HBE-TECC assay) [1]. CFTR corrector 8 exhibits hepatocyte clearance rate of 1250/775 L/hr/kg (human/rat)[1].

 Chemical & Physical Properties

Molecular Formula C29H27F2NO7
Molecular Weight 539.52
InChIKey KDOQEEMQPHIANX-REWPJTCUSA-N
SMILES COc1ccc2c(c1)OC(c1ccc(OC)c(OC)c1)CC2NC(=O)C1(c2ccc3c(c2)OC(F)(F)O3)CC1
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