Carboxypeptidase G2 (CPG2) Inhibitor

Modify Date: 2024-01-08 21:07:01

Carboxypeptidase G2 (CPG2) Inhibitor structure	Common Name	Carboxypeptidase G2 (CPG2) Inhibitor
	CAS Number	192203-60-4	Molecular Weight	313.32600
	Density	1.43	Boiling Point	N/A
	Molecular Formula	C₁₃H₁₅NO₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Carboxypeptidase G2 (CPG2) Inhibitor

Carboxypeptidase G2 (CPG2) Inhibitor is a novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents.

Name	(2S)-2-[(4-methoxyphenyl)sulfanylcarbonylamino]pentanedioic acid
Synonym	More Synonyms

Description	Carboxypeptidase G2 (CPG2) Inhibitor is a novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Carboxypeptidase Research Areas >> Cancer
References	[1]. Khan, Tariq H.; Eno-Amooquaye, Ebun A.; Searle, Frances et al. Novel Inhibitors of Carboxypeptidase G2 (CPG2): Potential Use in Antibody-Directed Enzyme Prodrug Therapy. Journal of Medicinal Chemistry (1999), 42(6), 951-956. [2]. Friedlos F, Lehouritis P, Ogilvie L et al. Attenuated Salmonella targets prodrug activating enzyme carboxypeptidase G2 to mouse melanoma and human breast and colon carcinomas for effective suicide gene therapy. Clin Cancer Res. 2008 Jul 1;14(13):4259-66. [3]. Schepelmann S, Ogilvie LM, Hedley D et al. Suicide gene therapy of human colon carcinoma xenografts using an armed oncolytic adenovirus expressing carboxypeptidase G2. Cancer Res. 2007 May 15;67(10):4949-55. [4]. Schepelmann S, Hallenbeck P, Ogilvie LM et al. Systemic gene-directed enzyme prodrug therapy of hepatocellular carcinoma using a targeted adenovirus armed with carboxypeptidase G2. Cancer Res. 2005 Jun 15;65(12):5003-8.

Description

Carboxypeptidase G2 (CPG2) Inhibitor is a novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents.

Related Catalog

Signaling Pathways >> Metabolic Enzyme/Protease >> Carboxypeptidase

Research Areas >> Cancer

References