Tumor Targeted Pro-Apoptotic Peptide trifluoroacetate salt
Modify Date: 2024-04-02 18:15:24
Tumor Targeted Pro-Apoptotic Peptide trifluoroacetate salt structure
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Common Name | Tumor Targeted Pro-Apoptotic Peptide trifluoroacetate salt | ||
|---|---|---|---|---|
| CAS Number | 1926163-30-5 | Molecular Weight | 2168.75 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C94H174N32O22S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tumor Targeted Pro-Apoptotic Peptide trifluoroacetate saltTumor targeted pro-apoptotic peptide (CNGRC-GG-D(KLAKLAK)2) is an anti-tumor peptide. Tumor targeted pro-apoptotic peptide disrupts mitochondrial membranes and promotes apoptosis, showing anticancer activity in mice[1]. |
| Name | Tumor Targeted Pro-Apoptotic Peptide trifluoroacetate salt |
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| Description | Tumor targeted pro-apoptotic peptide (CNGRC-GG-D(KLAKLAK)2) is an anti-tumor peptide. Tumor targeted pro-apoptotic peptide disrupts mitochondrial membranes and promotes apoptosis, showing anticancer activity in mice[1]. |
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| Related Catalog | |
| In Vitro | Tumor targeted pro-apoptotic peptide (10 µM; 0-20 min) induces mitochondrial swelling in DMECs[1]. Tumor targeted pro-apoptotic peptide (100 µM; 72 h) induces apoptosis in DMECs[1]. Cell Viability Assay[1] Cell Line: DMECs Concentration: 10 µM Incubation Time: 0-20 min Result: Induced considerable mitochondrial swelling at a concentration of 10 µM, and mild swelling was evident even at 3 µM. Apoptosis Analysis[1] Cell Line: DMECs Concentration: 100 µM Incubation Time: 72 h Result: Showed the classic morphological indicators of apoptosis, including nuclear condensation and fragmentation. |
| In Vivo | Tumor targeted pro-apoptotic peptide inhibits both primary tumor growth and metastasis in mice[1]. Animal Model: Tumor targeted pro-apoptotic peptide (250 µg/mice; tail vein injection; 250 µg a week for 17 weeks) inhibits both primary tumor growth and metastasis in mice[1]. Dosage: 250 µg/mice Administration: Tail vein injection; 250 µg a week for 17 weeks Result: Exhibited antitumor activity in vivo. |
| Molecular Formula | C94H174N32O22S2 |
|---|---|
| Molecular Weight | 2168.75 |
- Taiwan Oyi peptide Co. Ltd
- China
- Product Name: CYS-ASN-GLY-ARG-CYS-GLY-GLY-DLYS-DLEU-DALA-DLYS-DLEU-DALA-DLYS-DLYS-DLEU-DALA-DLYS-DLEU-DALA-DLYS
- Price: $Inquiry/1mg $Inquiry/100kg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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