DABCYL-γ-Abu-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2 structure
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Common Name | DABCYL-γ-Abu-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2 | ||
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CAS Number | 193475-71-7 | Molecular Weight | 1325.54 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C63H88N16O14S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of DABCYL-γ-Abu-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2TNO211 is a biological active peptide. (Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.This peptide is a highly soluble fluorogenic MMP substrate for MMP-2, 8, 12, 13 and 14, containing the MMP cleavable Gly-Leu bond and EDANS/DABCYL. Fluorogenic assays using TNO211 are sensitive and can detect MMP activity in culture medium from endothelial cells and untreated synovial fluid from patients. Abs/Em = 340/490 nm.) |
Name | DABCYL-(γ-Abu)-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2 |
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Synonym | More Synonyms |
Description | TNO211 is a biological active peptide. (Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.This peptide is a highly soluble fluorogenic MMP substrate for MMP-2, 8, 12, 13 and 14, containing the MMP cleavable Gly-Leu bond and EDANS/DABCYL. Fluorogenic assays using TNO211 are sensitive and can detect MMP activity in culture medium from endothelial cells and untreated synovial fluid from patients. Abs/Em = 340/490 nm.) |
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Related Catalog |
Molecular Formula | C63H88N16O14S |
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Molecular Weight | 1325.54 |
Exact Mass | 1309.63000 |
PSA | 459.01000 |
LogP | 8.07790 |
tno211 |
dabcyl-(g-abu)-pqgl-e(edans)ak-nh2 |
mmp substrate iii,fluorogenic |
dabcyl-gaba-pro-gln-gly-leu-glu(edans)-ala-lys-nh2 |
dabcyl-(g-abu)-pro-gln-gly-leu-glu(edans)-ala-lys-nh2 |
dabcyl-gaba-pqgl-e(edans)-ak-nh2 |
DABCYL-(γ-Abu)-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2 |