Methyl (2Z)-3-(4-hydroxyphenyl)acrylate

Modify Date: 2025-08-23 18:30:17

Methyl (2Z)-3-(4-hydroxyphenyl)acrylate Structure
Methyl (2Z)-3-(4-hydroxyphenyl)acrylate structure
Common Name Methyl (2Z)-3-(4-hydroxyphenyl)acrylate
CAS Number 19367-38-5 Molecular Weight 178.185
Density 1.2±0.1 g/cm3 Boiling Point 306.6±17.0 °C at 760 mmHg
Molecular Formula C10H10O3 Melting Point 138-140ºC
MSDS N/A Flash Point 132.8±13.7 °C

 Use of Methyl (2Z)-3-(4-hydroxyphenyl)acrylate


(E)-Methyl 4-coumarate (Methyl 4-hydroxycinnamate), found in several plants, such as green onion (Allium cepa) or noni (Morinda citrifolia L.) leaves. (E)-Methyl 4-coumarate cooperates with Carnosic Acid in inducing apoptosis and killing acute myeloid leukemia cells, but not normal peripheral blood mononuclear cells. Antioxidant and antimicrobial activity.

 Names

Name Methyl 4-hydroxycinnamate
Synonym More Synonyms

 Methyl (2Z)-3-(4-hydroxyphenyl)acrylate Biological Activity

Description (E)-Methyl 4-coumarate (Methyl 4-hydroxycinnamate), found in several plants, such as green onion (Allium cepa) or noni (Morinda citrifolia L.) leaves. (E)-Methyl 4-coumarate cooperates with Carnosic Acid in inducing apoptosis and killing acute myeloid leukemia cells, but not normal peripheral blood mononuclear cells. Antioxidant and antimicrobial activity.
Related Catalog
References

[1]. Trachtenberg A, et al. Synergistic Cytotoxicity of Methyl 4-Hydroxycinnamate and Carnosic Acid to Acute Myeloid Leukemia Cells via Calcium-Dependent Apoptosis Induction. Front Pharmacol. 2019 May 9;10:507.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 306.6±17.0 °C at 760 mmHg
Melting Point 138-140ºC
Molecular Formula C10H10O3
Molecular Weight 178.185
Flash Point 132.8±13.7 °C
Exact Mass 178.062988
PSA 46.53000
LogP 1.64
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.593
Storage condition Refrigerator

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36/37/39

 Synonyms

4-Hydroxy MethylesterCinnaMatc
METHYL 4-COUMARATE
4-hydroxycinnamic acid methyl ester
Methyl trans-p-Coumarate
METHYL P-HYDROXYCINNAMATE
Methyl (2Z)-3-(4-hydroxyphenyl)acrylate
Methyl trans-4-Hydroxycinnamate
Methyl 4-hydroxyphenylacrylate
METHYL COUMARATE
METHYL 3-HYDROXYCINNAMATE
trans-4-Hydroxycinnamic Acid Methyl Ester
(E)-Methyl 3-(4-hydroxyphenyl)acrylate
4-hydroxyphenyl-acrylic acid methyl ester
2-Propenoic acid, 3-(4-hydroxyphenyl)-, methyl ester, (2Z)-
Methyl trans-p-hydroxycinnaMate
MFCD00157167
trans-p-Coumaric Acid Methyl Ester
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