E3 ligase Ligand 1
Modify Date: 2024-01-03 13:52:10
E3 ligase Ligand 1 structure
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Common Name | E3 ligase Ligand 1 | ||
|---|---|---|---|---|
| CAS Number | 1948273-03-7 | Molecular Weight | 481.05 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H33ClN4O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of E3 ligase Ligand 1E3 ligase Ligand 1 is a Ligand for E3 Ligase extracted from patent WO/2017/030814A1 compound example 202, used in PROTAC technology. |
| Name | E3 ligase Ligand 1 |
|---|
| Description | E3 ligase Ligand 1 is a Ligand for E3 Ligase extracted from patent WO/2017/030814A1 compound example 202, used in PROTAC technology. |
|---|---|
| Related Catalog | |
| Target |
Ligand for E3 Ligase[1] |
| In Vitro | E3 ligase Ligand 1 is a VHL E3 ligase-binding ligand[1]. E3 ligase Ligand 1 is used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC. ARV-771, a small-molecule pan-BET degrader based on proteolysis-targeting chimera (PROTAC) technology, demonstrates dramatically improved efficacy in cellular models of castration-resistant prostate cancer (CRPC) as compared with BET inhibition[2]. |
| References |
[1]. WO/2017/030814A1 |
| Molecular Formula | C23H33ClN4O3S |
|---|---|
| Molecular Weight | 481.05 |
| Storage condition | 2-8℃ |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: E3 ligase Ligand 1
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: VHL ligand 2 hydrochloride
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: VHL ligand 2 hydrochloride
- Price: $650.0/1g $1100.0/2g $2200.0/5g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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Price: $300/100mg
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