Benzo(c)phenanthrene

Modify Date: 2024-01-02 18:53:59

Benzo(c)phenanthrene structure	Common Name	Benzo(c)phenanthrene
	CAS Number	195-19-7	Molecular Weight	228.288
	Density	1.2±0.1 g/cm3	Boiling Point	436.7±12.0 °C at 760 mmHg
	Molecular Formula	C₁₈H₁₂	Melting Point	158-160℃
	MSDS	Chinese USA	Flash Point	209.1±13.7 °C
	Symbol	GHS07	Signal Word	Warning

Name	Benzo[c]phenanthrene
Synonym	More Synonyms

Density	1.2±0.1 g/cm3
Boiling Point	436.7±12.0 °C at 760 mmHg
Melting Point	158-160℃
Molecular Formula	C₁₈H₁₂
Molecular Weight	228.288
Flash Point	209.1±13.7 °C
Exact Mass	228.093903
LogP	5.91
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.771

Benzo(c)phenanthrene MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DI8225000

CHEMICAL NAME :: Benzo(c)phenanthrene

CAS REGISTRY NUMBER :: 195-19-7

BEILSTEIN REFERENCE NO. :: 1909296

LAST UPDATED :: 199710

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C18-H12

MOLECULAR WEIGHT :: 228.30

WISWESSER LINE NOTATION :: L C6 B666J

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 940 mg/kg/39W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1220 mg/kg/51W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1270 mg/kg/53W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 80 umol/L

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 17,2237,1996 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,205,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,205,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW 85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77 Volume(issue)/page/year: Pc,4,1972

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302 + H312 + H332-H315-H319-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	20/21/22-36/37/38
Safety Phrases	26-37/39
RIDADR	UN 2811
RTECS	DI8225000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2902909090

HS Code	2902909090
Summary	2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

Benzo[c]phenanthrene adducts and nogalamycin inhibit DNA transesterification by vaccinia topoisomerase.

J. Biol. Chem. 279(22) , 23335-42, (2004)

Vaccinia DNA topoisomerase forms a covalent DNA-(3'-phosphotyrosyl)-enzyme intermediate at a specific target site 5'-C(+5)C(+4)C(+3)T(+2)T(+1)p downward arrow N(-1) in duplex DNA. Here we study the ef...

In vitro and in vivo modulations of benzo[c]phenanthrene-DNA adducts by DNA mismatch repair system.

Nucleic Acids Res. 31(22) , 6428-34, (2003)

Benzo[c]phenanthrene dihydrodiol epoxide (B[c] PhDE) is well known as an important environmental chemical carcinogen that preferentially modifies DNA in adenine residues. However, the molecular mechan...

Structure/reactivity relationships in the benzo[c]phenanthrene skeleton: stable ion and electrophilic substitution (nitration, bromination) study of substituted analogues, novel carbocations and substituted derivatives.

J. Org. Chem. 72(9) , 3232-41, (2007)

A series of novel carbocations were generated by low-temperature protonation of substituted benzo[c]phenanthrenes, B[c]Phs, and their charge delocalization pathways were elucidated by NMR on the basis...

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Benzo(c)phenanthrene

tetrahelicene

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Benzo(c)phenanthrene
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: benzo[c]phenanthrene
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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