Fosclevudine alafenamide

Modify Date: 2025-08-25 21:21:27

Fosclevudine alafenamide Structure
Fosclevudine alafenamide structure
Common Name Fosclevudine alafenamide
CAS Number 1951476-79-1 Molecular Weight 529.45
Density N/A Boiling Point N/A
Molecular Formula C22H29FN3O9P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fosclevudine alafenamide


Fosclevudine alafenamide (Compound EIDD-02173) is an antiviral agent with an EC50 of 1.71 μM against HBV[1].

 Names

Name Fosclevudine alafenamide

 Fosclevudine alafenamide Biological Activity

Description Fosclevudine alafenamide (Compound EIDD-02173) is an antiviral agent with an EC50 of 1.71 μM against HBV[1].
Related Catalog
Target

EC50: 1.71 μM (HBV)[1]

In Vitro Fosclevudine alafenamide (Compound EIDD-02173) shows cytotoxicity against CEM, A204, IEC-6 and H9c cells[1]. Cell Cytotoxicity Assay[1] Cell Line: CEM, A204, IEC-6, H9c Concentration: 0-400 μM Incubation Time: 6 days Result: Showed cytotoxicity with CC50 values of 140, 330, 307 and 344 μM against CEM, A204, IEC-6 and H9c cells, respectively.
References

[1]. Abel De La Rosa, et al. Phosphoramidates for the treatment of hepatitis b virus. WO2017223421A1.

 Chemical & Physical Properties

Molecular Formula C22H29FN3O9P
Molecular Weight 529.45
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