Fosclevudine alafenamide
Modify Date: 2025-08-25 21:21:27
Fosclevudine alafenamide structure
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Common Name | Fosclevudine alafenamide | ||
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| CAS Number | 1951476-79-1 | Molecular Weight | 529.45 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H29FN3O9P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Fosclevudine alafenamideFosclevudine alafenamide (Compound EIDD-02173) is an antiviral agent with an EC50 of 1.71 μM against HBV[1]. |
| Name | Fosclevudine alafenamide |
|---|
| Description | Fosclevudine alafenamide (Compound EIDD-02173) is an antiviral agent with an EC50 of 1.71 μM against HBV[1]. |
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| Related Catalog | |
| Target |
EC50: 1.71 μM (HBV)[1] |
| In Vitro | Fosclevudine alafenamide (Compound EIDD-02173) shows cytotoxicity against CEM, A204, IEC-6 and H9c cells[1]. Cell Cytotoxicity Assay[1] Cell Line: CEM, A204, IEC-6, H9c Concentration: 0-400 μM Incubation Time: 6 days Result: Showed cytotoxicity with CC50 values of 140, 330, 307 and 344 μM against CEM, A204, IEC-6 and H9c cells, respectively. |
| References |
[1]. Abel De La Rosa, et al. Phosphoramidates for the treatment of hepatitis b virus. WO2017223421A1. |
| Molecular Formula | C22H29FN3O9P |
|---|---|
| Molecular Weight | 529.45 |
| InChIKey | FTMNZJASLMPPNW-MHFVGYLCSA-N |
| SMILES | Cc1cn(C2OC(COP(=O)(NC(C)C(=O)OC(C)C)Oc3ccccc3)C(O)C2F)c(=O)[nH]c1=O |