SJ-3366

Modify Date: 2024-01-17 00:55:48

SJ-3366 structure	Common Name	SJ-3366
	CAS Number	195720-26-4	Molecular Weight	352.42700
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₄N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SJ-3366

SJ-3366 (IQP-0410) is a potent inhibitor of HIV nonnucleoside reverse transcriptase[1]. SJ-3366 (IQP-0410) inhibits HIV at sub-nanomolar concentrations primarily through a typical non-nucleoside mechanism[2].

Name	1-(cyclopent-3-en-1-ylmethyl)-6-(3,5-dimethylbenzoyl)-5-ethylpyrimidine-2,4-dione
Synonym	More Synonyms

Description	SJ-3366 (IQP-0410) is a potent inhibitor of HIV nonnucleoside reverse transcriptase[1]. SJ-3366 (IQP-0410) inhibits HIV at sub-nanomolar concentrations primarily through a typical non-nucleoside mechanism[2].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Inflammation/Immunology
Target	nonnucleoside reverse transcriptase[1]
References	[1]. Ham AS, Lustig W, Yang L, Boczar A, Buckheit KW, Buckheit RW Jr. In vitro and ex vivo evaluations on transdermal delivery of the HIV inhibitor IQP-0410. PLoS One. 2013;8(9):e75306. [2]. Buckheit RW Jr, Watson Buckheit K, Sturdevant CB, Buckheit RW 3rd. Selection and characterization of viruses resistant to the dual acting pyrimidinedione entry and non-nucleoside reverse transcriptase inhibitor IQP-0410. Antiviral Res. 2013;100(2):382-391.

Molecular Formula	C₂₁H₂₄N₂O₃
Molecular Weight	352.42700
Exact Mass	352.17900
PSA	72.19000
LogP	3.32530

Hazard Codes	Xi

IQP0410

Nab 2F5

Nab 2G12

SJ-3366

SJ-3366

Use of SJ-3366

Names

SJ-3366 Biological Activity

Chemical & Physical Properties

Safety Information

Synonyms