Corifollitropin alfa
Modify Date: 2024-01-05 11:04:14
Corifollitropin alfa structure
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Common Name | Corifollitropin alfa | ||
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| CAS Number | 195962-23-3 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Corifollitropin alfaCorifollitropin alfa (Org 36286) is a long-acting recombinant follicle-stimulating hormone (FSH) analog. Corifollitropin alfa is a FSH Receptor agonist with an EC50 of 5.0 pM. Corifollitropin alfa stimulates ovulation and can be used in the research of infertility[1][2][3]. |
| Name | Corifollitropin alfa |
|---|
| Description | Corifollitropin alfa (Org 36286) is a long-acting recombinant follicle-stimulating hormone (FSH) analog. Corifollitropin alfa is a FSH Receptor agonist with an EC50 of 5.0 pM. Corifollitropin alfa stimulates ovulation and can be used in the research of infertility[1][2][3]. |
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| Related Catalog | |
| Target |
FSH Receptor[2] |
| In Vivo | Corifollitropin alfa (20 μg/kg, s.c., single injection) shows a t1/2 of 17.3 h and Cmax of 3.2 ng/mL/μg/kg in female Wistar rats[2]. Corifollitropin alfa (2.5-40 μg/kg, s.c.) stimulates superovulation in rats[2]. Corifollitropin alfa (3 µg, supplemented with hCG, s.c.) increases ovulation rate and recovered embryos in rabbits[3]. Animal Model: Rats[2] Dosage: 2.5, 5, 10, 20, 40 μg/kg. Administration: Subcutaneous injection (s.c), four injections given on 2 subsequent days (0, 8, 24, and 32 h). Result: Increased the number of ovulated oocytes, reached maximal value at 20 μg/kg. |
| References |
| No Any Chemical & Physical Properties |