Farglitazar

Modify Date: 2024-01-10 10:14:14

Farglitazar Structure
Farglitazar structure
Common Name Farglitazar
CAS Number 196808-45-4 Molecular Weight 546.61200
Density N/A Boiling Point 793.7ºC at 760 mmHg
Molecular Formula C34H30N2O5 Melting Point N/A
MSDS N/A Flash Point 433.8ºC

 Use of Farglitazar


Farglitazar is a PPARγ agonist that has significant therapeutic benefits such as glycemic control in type 2 diabetic patients.

 Names

Name (2S)-2-(2-benzoylanilino)-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]propanoic acid
Synonym More Synonyms

 Farglitazar Biological Activity

Description Farglitazar is a PPARγ agonist that has significant therapeutic benefits such as glycemic control in type 2 diabetic patients.
Related Catalog
References

[1]. Chen L, Yang B, McNulty JA, et al. GI262570, a peroxisome proliferator-activated receptor {gamma} agonist, changes electrolytes and water reabsorption from the distal nephron in rats. J Pharmacol Exp Ther. 2005;312(2):718-725.

 Chemical & Physical Properties

Boiling Point 793.7ºC at 760 mmHg
Molecular Formula C34H30N2O5
Molecular Weight 546.61200
Flash Point 433.8ºC
Exact Mass 546.21500
PSA 101.66000
LogP 6.68330
Vapour Pressure 1.45E-26mmHg at 25°C
Index of Refraction 1.639

 Synthetic Route

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Farglitazar Structure

Farglitazar

CAS#:196808-45-4

Literature: Henke, Brad R.; Blanchard, Steven G.; Brackeen, Marcus F.; Brown, Kathleen K.; Cobb, Jeff E.; Collins, Jon L.; Harrington Jr., W. Wallace; Hashim, Mir A.; Hull-Ryde, Emily A.; Kaldor, Istvan; Kliewer, Steven A.; Lake, Debra H.; Leesnitzer, Lisa M.; Lehmann, Juergen M.; Lenhard, James M.; Orband-Miller, Lisa A.; Miller, John F.; Mook Jr., Robert A.; Noble, Stewart A.; Oliver Jr., William; Parks, Derek J.; Plunket, Kelli D.; Szewczyk, Jerzy R.; Willson, Timothy M. Journal of Medicinal Chemistry, 1998 , vol. 41, # 25 p. 5020 - 5036

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Farglitazar Structure

Farglitazar

CAS#:196808-45-4

Literature: Collins, Jon L.; Blanchard, Steven G.; Boswell, G. Evan; Charifson, Paul S.; Cobb, Jeff E.; Henke, Brad R.; Hull-Ryde, Emily A.; Kazmierski, Wieslaw M.; Lake, Debra H.; Leesnitzer, Lisa M.; Lehmann, Juergen; Lenhard, James M.; Orband-Miller, Lisa A.; Gray-Nunez, Yolanda; Parks, Derek J.; Plunkett, Kelli D.; Tong, Wei-Qin Journal of Medicinal Chemistry, 1998 , vol. 41, # 25 p. 5037 - 5054

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Farglitazar Structure

Farglitazar

CAS#:196808-45-4

Literature: Henke, Brad R.; Blanchard, Steven G.; Brackeen, Marcus F.; Brown, Kathleen K.; Cobb, Jeff E.; Collins, Jon L.; Harrington Jr., W. Wallace; Hashim, Mir A.; Hull-Ryde, Emily A.; Kaldor, Istvan; Kliewer, Steven A.; Lake, Debra H.; Leesnitzer, Lisa M.; Lehmann, Juergen M.; Lenhard, James M.; Orband-Miller, Lisa A.; Miller, John F.; Mook Jr., Robert A.; Noble, Stewart A.; Oliver Jr., William; Parks, Derek J.; Plunket, Kelli D.; Szewczyk, Jerzy R.; Willson, Timothy M. Journal of Medicinal Chemistry, 1998 , vol. 41, # 25 p. 5020 - 5036

~%

Farglitazar Structure

Farglitazar

CAS#:196808-45-4

Literature: Henke, Brad R.; Blanchard, Steven G.; Brackeen, Marcus F.; Brown, Kathleen K.; Cobb, Jeff E.; Collins, Jon L.; Harrington Jr., W. Wallace; Hashim, Mir A.; Hull-Ryde, Emily A.; Kaldor, Istvan; Kliewer, Steven A.; Lake, Debra H.; Leesnitzer, Lisa M.; Lehmann, Juergen M.; Lenhard, James M.; Orband-Miller, Lisa A.; Miller, John F.; Mook Jr., Robert A.; Noble, Stewart A.; Oliver Jr., William; Parks, Derek J.; Plunket, Kelli D.; Szewczyk, Jerzy R.; Willson, Timothy M. Journal of Medicinal Chemistry, 1998 , vol. 41, # 25 p. 5020 - 5036

 Synonyms

N-(o-Benzoylphenyl)-O-(2-(5-methyl-2-phenyl-4-oxazolyl)ethyl)-L-tyrosine
L-Tyrosine,N-(2-benzoylphenyl)-o-(2-(5-methyl-2-phenyl-4-oxazolyl)ethyl)
Farglitazar
N-(2-benzoylphenyl)-O-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yI)ethyl]-L-tyrosine
(2S)-((2-benzoylphenyl)amino)-3-{4-[2-(5-methyl-2-phenyloxazol-4-yl)ethoxy]phenyl}-propionic acid
2-(2-BENZOYL-PHENYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID
Top Suppliers:I want be here
  • DC Chemicals Limited
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  • Product Name: Farglitazar
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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