Chrysoeriol-7-O-glucoside

Modify Date: 2024-01-02 17:21:13

Chrysoeriol-7-O-glucoside Structure
Chrysoeriol-7-O-glucoside structure
Common Name Chrysoeriol-7-O-glucoside
CAS Number 19993-32-9 Molecular Weight 462.404
Density 1.609 Boiling Point 801.6±65.0 °C at 760 mmHg
Molecular Formula C22H22O11 Melting Point 176-179 ºC
MSDS N/A Flash Point 281.0±27.8 °C

 Use of Chrysoeriol-7-O-glucoside


Thermopsoside is a flavone derivative isolated from Aspalathus linearis. Thermopsoside exhibits inhibitory effects on CYP450 isozymes with IC50 values of 6.0 μM, 9.5 μM, 12.0 μM, 32.0 μM, for CYP3A4, CYP2C19, CYP2D6 and CYP2C9, respectively[1].

 Names

Name 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
Synonym More Synonyms

 Chrysoeriol-7-O-glucoside Biological Activity

Description Thermopsoside is a flavone derivative isolated from Aspalathus linearis. Thermopsoside exhibits inhibitory effects on CYP450 isozymes with IC50 values of 6.0 μM, 9.5 μM, 12.0 μM, 32.0 μM, for CYP3A4, CYP2C19, CYP2D6 and CYP2C9, respectively[1].
Related Catalog
References

[1]. Omer I Fantoukh, et al. Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea ( Aspalathus linearis) through Interaction with CYP, PXR, and P-gp. J Agric Food Chem. 2019 May 1;67(17):4967-4975.

 Chemical & Physical Properties

Density 1.609
Boiling Point 801.6±65.0 °C at 760 mmHg
Melting Point 176-179 ºC
Molecular Formula C22H22O11
Molecular Weight 462.404
Flash Point 281.0±27.8 °C
Exact Mass 462.116211
PSA 179.28000
LogP -0.68
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.695

 Safety Information

Hazard Codes Xi

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

4H-1-Benzopyran-4-one, 7-(D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-
5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-oxo-4H-chromen-7-yl D-glucopyranoside
Chrysoeriol 7-O-glucoside