Ac-RYYRIK-NH2 TFA
Ac-RYYRIK-NH2 TFA structure
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Common Name | Ac-RYYRIK-NH2 TFA | ||
|---|---|---|---|---|
| CAS Number | 200959-48-4 | Molecular Weight | 939.115 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C44H70N14O9 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of Ac-RYYRIK-NH2 TFAAc-RYYRIK-NH2 is a potent and partial agonist on ORL1 transfected in CHO cells (Kd=1.5 nM) and behaves as a endogenous ligand of ORL1. Ac-RYYRIK-NH2 is a specific antagonist for the activation of G protein and competitively antagonizes the stimulation of [35S]-GTPgS binding to G proteins by nociceptin/orphanin FQ (noc/OFQ) in membranes and sections of rat brain[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Ac-RYYRIK-NH2 |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Ac-RYYRIK-NH2 is a potent and partial agonist on ORL1 transfected in CHO cells (Kd=1.5 nM) and behaves as a endogenous ligand of ORL1. Ac-RYYRIK-NH2 is a specific antagonist for the activation of G protein and competitively antagonizes the stimulation of [35S]-GTPgS binding to G proteins by nociceptin/orphanin FQ (noc/OFQ) in membranes and sections of rat brain[1]. |
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| Related Catalog | |
| Target |
Kd: 1.5 nM (ORL1 transfected in CHO cells)[1] |
| In Vivo | Ac-RYYRIK-NH2 (intracerebroventricularly (i.c.v.) inhibits spontaneous locomotor activity in mice with an ID50 of 0.07 nmol. Co-administration of noc/OFQ and Ac-RYYRIK-NH2 lead to additive effects in Male Swiss mice[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C44H70N14O9 |
| Molecular Weight | 939.115 |
| Exact Mass | 938.545044 |
| PSA | 407.97000 |
| LogP | -1.04 |
| Index of Refraction | 1.644 |
| InChIKey | WBBBVZGQADABSU-RERZDIOCSA-N |
| SMILES | CCC(C)C(NC(=O)C(CCCN=C(N)N)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCN=C(N)N)NC(C)=O)C(=O)NC(CCCCN)C(N)=O |
| Storage condition | -20°C |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| N-acetyl-N-(diaminomethylidene)-L-ornithyl-L-tyrosyl-L-tyrosyl-N-(diaminomethylidene)-L-ornithyl-L-isoleucyl-L-lysinamide |
| Ac-RYYRIK amide |
| AC-ARG-TYR-TYR-ARG-ILE-LYS-NH2 |
| N-Acetyl-N-(diaminomethylene)-L-ornithyl-L-tyrosyl-L-tyrosyl-N-(diaminomethylene)-L-ornithyl-L-isoleucyl-L-lysinamide |
| ACETYL-RYYRIK,AMIDE |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the polar surface area (PSA) of Ac-RYYRIK-NH2? |
| A: Polar surface area (PSA) of Ac-RYYRIK-NH2 is 407.97000. |
| Q: What is the English name of Ac-RYYRIK-NH2? |
| A: The English name of Ac-RYYRIK-NH2 is Ac-RYYRIK-NH2. |
| Q: What is the molecular formula of Ac-RYYRIK-NH2? |
| A: Molecular formula of Ac-RYYRIK-NH2 is C44H70N14O9. |
| Q: What is the CAS number of Ac-RYYRIK-NH2? |
| A: CAS number of Ac-RYYRIK-NH2 is 200959-48-4. |
| Q: What is the SMILES notation of Ac-RYYRIK-NH2? |
| A: SMILES notation of Ac-RYYRIK-NH2 is CCC(C)C(NC(=O)C(CCCN=C(N)N)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCN=C(N)N)NC(C)=O)C(=O)NC(CCCCN)C(N)=O. |
| Q: What English synonyms does Ac-RYYRIK-NH2 have? |
| A: English synonyms of Ac-RYYRIK-NH2: N-acetyl-N-(diaminomethylidene)-L-ornithyl-L-tyrosyl-L-tyrosyl-N-(diaminomethylidene)-L-ornithyl-L-isoleucyl-L-lysinamide, Ac-RYYRIK amide, AC-ARG-TYR-TYR-ARG-ILE-LYS-NH2, N-Acetyl-N-(diaminomethylene)-L-ornithyl-L-tyrosyl-L-tyrosyl-N-(diaminomethylene)-L-ornithyl-L-isoleucyl-L-lysinamide, ACETYL-RYYRIK,AMIDE. |
| Q: What is the Chinese name of 200959-48-4? |
| A: Chinese name of 200959-48-4 is AC-ARG-TYR-TYR-ARG-ILE-LYS-NH2. |
| Q: What are the storage conditions for Ac-RYYRIK-NH2? |
| A: Storage conditions for Ac-RYYRIK-NH2: -20°C. |
| Q: What is the molecular weight of Ac-RYYRIK-NH2? |
| A: Molecular weight of Ac-RYYRIK-NH2 is 939.115. |
| Q: What is the InChIKey of Ac-RYYRIK-NH2? |
| A: InChIKey of Ac-RYYRIK-NH2 is WBBBVZGQADABSU-RERZDIOCSA-N. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |