N33-TEG-COOH

Modify Date: 2024-01-10 18:55:39

N33-TEG-COOH Structure
N33-TEG-COOH structure
Common Name N33-TEG-COOH
CAS Number 201467-81-4 Molecular Weight 277.27400
Density N/A Boiling Point N/A
Molecular Formula C10H19N3O6 Melting Point N/A
MSDS N/A Flash Point -27.4 °F
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Use of N33-TEG-COOH


N33-TEG-COOH is a PROTAC linker containing four polyethylene glycol (PEG) units.

 Names

Name N3-Teg-COOH
Synonym More Synonyms

 N33-TEG-COOH Biological Activity

Description N33-TEG-COOH is a PROTAC linker containing four polyethylene glycol (PEG) units.
Related Catalog
Target

PROTAC linker[1]

In Vitro N33-TEG-COOH is a long linker extracted from Reference PMID: 26035625, Compound 7. A PROTAC is a heterobifunctional compound that contains two ligands connected by a linker unit. One ligand binds an E3 ubiquitin ligase protein, while the other ligand binds to the target protein of interest, thereby bringing the ligase and the target in close proximity[1].
References

[1]. Zengerle M, et al. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. ACS Chem Biol. 2015 Aug 21;10(8):1770-7.

 Chemical & Physical Properties

Molecular Formula C10H19N3O6
Molecular Weight 277.27400
Exact Mass 277.12700
PSA 123.97000
Storage condition 2-8℃

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H315
Precautionary Statements P210
RIDADR UN 2398 3 / PGII
Flash Point(F) -27.4 °F
Flash Point(C) -33 °C

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethanoic acid
N33-TEG-COOH
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