phycocyanobilin

Modify Date: 2024-01-03 14:24:19

phycocyanobilin structure	Common Name	phycocyanobilin
	CAS Number	20298-86-6	Molecular Weight	586.67800
	Density	1.31±0.1 g/cm3	Boiling Point	892.1±65.0 °C
	Molecular Formula	C₃₃H₃₈N₄O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of phycocyanobilin

Phycocyanobilin, an orally active antioxidative agent, is an effective scavenger for various reactive oxygen species. Phycocyanobilin can be used for the research of Alzheimer’s disease[1][2][3].

Name	(3E)-phycocyanobilin
Synonym	More Synonyms

Description	Phycocyanobilin, an orally active antioxidative agent, is an effective scavenger for various reactive oxygen species. Phycocyanobilin can be used for the research of Alzheimer’s disease[1][2][3].
Related Catalog	Research Areas >> Neurological Disease
In Vitro	Phycocyanobilin (100 μM; 0-250 min) 抑制亚油酸甲酯的过氧化，并产生较长的诱导期[1]。 Phycocyanobilin (1 mM; 0-300 min) 抑制脂质体的氧化[1]。
In Vivo	Phycocyanobilin (15 mg/kg; p.o.; in diet for 2 weeks) 在 2 型糖尿病小鼠中显示抗氧化作用[3]。 Animal Model: Male C57BL/Ks J db/db mice, a rodent model for type 2 diabetes[3] Dosage: 15 mg/kg Administration: In diet for 2 weeks Result: Significantly decreased blood glucose levels. Normalized the increases in urinary 8-OHdG and 8-epi-PGF2α levels, renal oxidative stress markers evaluated by renal 8-OHdG staining and DHE staining, Nox4 mRNA, and protein expression, as well as the mRNA levels of other NAD(P)H oxidase components, inflammatory markers and HO-1.
References	[1]. Hirata T, et al. Antioxidant activities of phycocyanobilin prepared from Spirulina platensis. Journal of Applied Phycology, 2000, 12: 435-439. [2]. Matamoros BP, et al. Nutraceutical and therapeutic potential of Phycocyanobilin for treating Alzheimer's disease. J Biosci. 2021;46:42. [3]. Zheng J, et al. Phycocyanin and phycocyanobilin from Spirulina platensis protect against diabetic nephropathy by inhibiting oxidative stress. Am J Physiol Regul Integr Comp Physiol. 2013 Jan 15;304(2):R110-20.

Density	1.31±0.1 g/cm3
Boiling Point	892.1±65.0 °C
Molecular Formula	C₃₃H₃₈N₄O₆
Molecular Weight	586.67800
Exact Mass	586.27900
PSA	164.71000
LogP	3.12850

Hazard Codes	Xi
HS Code	3203001990

HS Code	3203001990

3-[(2Z,5E)-2-[[3-(2-carboxyethyl)-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-2-yl]methylidene]-5-[(4-ethyl-3-methyl-5-oxopyrrol-2-yl)methylidene]-4-methylpyrrol-3-yl]propanoic acid

phycocyanobilin

3,3'-(18-ethyl-3-ethylidene-2,7,13,17-tetramethyl-1,19-dioxo-1,2,3,19,22,24-hexahydro-21H-biline-8,12-diyl)-bis-propionic acid

Phycobilin

21H-Biline-8,12-dipropanoic acid,18-ethyl-3-ethylidene-1,2,3,19,22,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-,(2R,3E)