stigmast-5-en-7-on-3§-ol

Modify Date: 2026-07-17 08:00:07

stigmast-5-en-7-on-3§-ol Structure
stigmast-5-en-7-on-3§-ol structure
Common Name stigmast-5-en-7-on-3§-ol
CAS Number 2034-74-4 Molecular Weight 428.690
Density 1.0±0.1 g/cm3 Boiling Point 536.1±29.0 °C at 760 mmHg
Molecular Formula C29H48O2 Melting Point N/A
MSDS N/A Flash Point 226.1±16.9 °C

 Use of stigmast-5-en-7-on-3§-ol


7-Ketositosterol is a phytosterol isolated from the fruits of the mulberry tree (Morus alba L.). 7-Ketositosterol can significantly inhibit Cisplatin (HY-17394)-induced apoptosis in LLC-PK1 cells and has the potential to improve Cisplatin-induced nephrotoxicity[1].

 Names

Name (3S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-3-hydroxy-10,13-dimethyl-1,2,3,4,8,9,10,11,12,13,14,15,16,17-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one
Synonym More Synonyms

 stigmast-5-en-7-on-3§-ol Biological Activity

Description 7-Ketositosterol is a phytosterol isolated from the fruits of the mulberry tree (Morus alba L.). 7-Ketositosterol can significantly inhibit Cisplatin (HY-17394)-induced apoptosis in LLC-PK1 cells and has the potential to improve Cisplatin-induced nephrotoxicity[1].
Related Catalog
References

[1]. Lee D, et al. Identification of Renoprotective Phytosterols from Mulberry (Morus alba) Fruit against Cisplatin-Induced Cytotoxicity in LLC-PK1 Kidney Cells. Plants (Basel). 2021 Nov 17;10(11):2481.  

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 536.1±29.0 °C at 760 mmHg
Molecular Formula C29H48O2
Molecular Weight 428.690
Flash Point 226.1±16.9 °C
Exact Mass 428.365417
PSA 37.30000
LogP 8.45
Vapour Pressure 0.0±3.2 mmHg at 25°C
Index of Refraction 1.526
InChIKey ICFXJOAKQGDRCT-ZIHMWMKCSA-N
SMILES CCC(CCC(C)C1CCC2C3C(=O)C=C4CC(O)CCC4(C)C3CCC12C)C(C)C

 Safety Information

Hazard Codes Xi

 stigmast-5-en-7-on-3§-olBioassay

View more

Name: Antitubercular activity against Mycobacterium tuberculosis H37Rv after 2 weeks by aga...
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL959623
Name: Cytotoxicity against human MDA-MB-231 cells
Source: ChEMBL
Target: MDA-MB-231
External Id: CHEMBL2379890
Name: Cytotoxicity against human A549 cells
Source: ChEMBL
Target: A549
External Id: CHEMBL2379889
Name: Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induc...
Source: ChEMBL
Target: BV-2
External Id: CHEMBL4047079
Name: Cytotoxicity against human Hep3B cells
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL2379893
Name: Cytotoxicity against human HepG2 cells
Source: ChEMBL
Target: HepG2
External Id: CHEMBL2379892
Name: Cytotoxicity against human MCF7 cells
Source: ChEMBL
Target: MCF7
External Id: CHEMBL2379891
Name: Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced EBV-early antigen activati...
Source: ChEMBL
Target: N/A
External Id: CHEMBL945506
Name: Cytotoxicity against human HT-29 cells after 48 hrs by Alamar blue assay
Source: ChEMBL
Target: HT-29
External Id: CHEMBL1286346
Name: Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced EBV-early antigen activati...
Source: ChEMBL
Target: N/A
External Id: CHEMBL945505
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 Synonyms

stigmast-5-en-7-on-3§-ol
3§-hydroxystigmast-5-en-7-one
(3β)-3-Hydroxystigmast-5-en-7-one
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