EDTA-d12
Modify Date: 2024-01-02 18:57:41
EDTA-d12 structure
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Common Name | EDTA-d12 | ||
|---|---|---|---|---|
| CAS Number | 203806-08-0 | Molecular Weight | 304.317 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 614.2±55.0 °C at 760 mmHg | |
| Molecular Formula | C10H4D12N2O8 | Melting Point | 250ºC (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 325.2±31.5 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of EDTA-d12EDTA-d12 is the deuterium labeled Ethylenediaminetetraacetic acid[1]. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds[2][3][4]. |
| Name | 2-[[2-[bis[carboxy(dideuterio)methyl]amino]-1,1,2,2-tetradeuterioethyl]-[carboxy(dideuterio)methyl]amino]-2,2-dideuterioacetic acid |
|---|---|
| Synonym | More Synonyms |
| Description | EDTA-d12 is the deuterium labeled Ethylenediaminetetraacetic acid[1]. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds[2][3][4]. |
|---|---|
| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 614.2±55.0 °C at 760 mmHg |
| Melting Point | 250ºC (dec.)(lit.) |
| Molecular Formula | C10H4D12N2O8 |
| Molecular Weight | 304.317 |
| Flash Point | 325.2±31.5 °C |
| Exact Mass | 304.165985 |
| PSA | 155.68000 |
| LogP | -0.43 |
| Vapour Pressure | 0.0±3.8 mmHg at 25°C |
| Index of Refraction | 1.580 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Codes | Xi |
| RIDADR | UN 3077 9 / PGIII |
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Metabonomic Changes Associated with Atherosclerosis Progression for LDLR(-/-) Mice.
J. Proteome Res. 14 , 2237-54, (2015) Atherosclerosis resulting from hyperlipidemia causes many serious cardiovascular diseases. To understand the systems changes associated with pathogenesis and progression of atherosclerosis, we compreh... |
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Mammalian production of an isotopically enriched outer domain of the HIV-1 gp120 glycoprotein for NMR spectroscopy.
J. Biomol. NMR 50 , 197-207, (2011) NMR spectroscopic characterization of the structure or the dynamics of proteins generally requires the production of samples isotopically enriched in (15)N, (13)C, or (2)H. The bacterial expression sy... |
| 2,2',2'',2'''-[(H)Ethane-1,2-diyldinitrilo]tetra(H)acetic acid |
| 2,2',2'',2'''-[(H)-1,2-Ethanediyldinitrilo]tetra(H)acetic acid |
| Ethylenediaminetetraacetic-d12 acid |
| MFCD00144285 |
| EDTA-d12 |