Liraglutide
Liraglutide structure
|
Common Name | Liraglutide | ||
|---|---|---|---|---|
| CAS Number | 204656-20-2 | Molecular Weight | 3751.20000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C172H265N43O51 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LiraglutideLiraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | liraglutide |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus. |
|---|---|
| Related Catalog | |
| Target |
GLP-1 receptor[1] |
| In Vitro | Liraglutide binds to the same receptors as does the endogenous metabolic hormone GLP-1 that stimulates insulin secretion. Liraglutide is an injectable drug for the treatment of type 2 diabetes, also can be used to treat obesity in adults with some related comorbidity. Liraglutide activated AMPK/SREBP1 pathway in oxLDL-stimulated Raw264.7 cells[1]. |
| Cell Assay | Raw264.7 macrophage cells are cultured in Dulbecco's modified Eagle's medium supplemented with 10% fetal bovine serum in a humidified 37°C incubator with 5% CO2. The cells are incubated with oxLDL (50 μg/mL), Liraglutide (0.1, 0.5, 1 and 2 nM) or Exendin-3 (9-39) (1, 10 and 100 nM) alone, or in combination[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C172H265N43O51 |
|---|---|
| Molecular Weight | 3751.20000 |
| Exact Mass | 3748.95000 |
| PSA | 1513.76000 |
| LogP | 6.12960 |
| InChIKey | YSDQQAXHVYUZIW-QCIJIYAXSA-N |
| SMILES | CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCCC(NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(N)=O)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(N)Cc1cnc[nH]1)C(C)O)C(C)O)C(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(=O)NC(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)O)C(C)C)C(C)CC)C(=O)O |
| Storage condition | -20°C |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| liraglutide |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What English synonyms does liraglutide have? |
| A: English synonyms of liraglutide: liraglutide. |
| Q: What is the CAS number of liraglutide? |
| A: CAS number of liraglutide is 204656-20-2. |
| Q: What is the molecular formula of liraglutide? |
| A: Molecular formula of liraglutide is C172H265N43O51. |
| Q: What is the InChIKey of liraglutide? |
| A: InChIKey of liraglutide is YSDQQAXHVYUZIW-QCIJIYAXSA-N. |
| Q: What are the storage conditions for liraglutide? |
| A: Storage conditions for liraglutide: -20°C. |
| Q: What are the uses of liraglutide? |
| A: Main uses of liraglutide: Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus. |
| Q: What is the polar surface area (PSA) of liraglutide? |
| A: Polar surface area (PSA) of liraglutide is 1513.76000. |
| Q: What is the LogP of liraglutide? |
| A: LogP of liraglutide is 6.12960. |
| Q: What is the molecular weight of liraglutide? |
| A: Molecular weight of liraglutide is 3751.20000. |
| Q: What is the English name of liraglutide? |
| A: The English name of liraglutide is liraglutide. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Henan Tianfu Chemical Co., Ltd. |