204656-20-2
204656-20-2 structure
- Name: Liraglutide
- Chemical Name: liraglutide
- CAS Number: 204656-20-2
- Molecular Formula: C172H265N43O51
- Molecular Weight: 3751.20000
- Catalog: API Hormone and endocrine-regulating drugs Pancreatic hormones and other blood sugar regulating drugs
- Create Date: 2018-05-10 08:00:00
- Modify Date: 2026-07-01 06:38:36
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Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.
| Name | liraglutide |
|---|---|
| Synonyms |
Liraglutide /Liraglutide Acetate
(Lys(γ-Glu-palmitoyl)26,g34)-GLP-1 Liraglutidum [inn-latin] (4S)-5-[[(5S)-5-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[2-[[(2S Liaglutide Liraglutide, (Lys(γ-Glu-palmitoyl)26,g34)-GLP-1 ade Liraglutide Liraglutide //BP Glycine, L-histidyl-L Liraglutide GLP-1 Liraglutide, glucagon-like ptide-1(GLP-1) rector agonist Liraglutide [usan:inn] Liraglutide-d8 Tri-TrifluoroacetateQ: What is Liraglutide-d8 Tri-Trifluoroacetate Q: What is the CAS Number of Liraglutide-d8 Tri-Trifluoroacetate Q: What is the storage condition of Liraglutide-d8 Tri-Trifluoroacetate Liraglutide injection Liraglutide Acetate Liraglutide-d8 Tri-Trifluoroacetate Liraglutidum (4S)-5-[[(5S)-5-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-5-hyd Liraglutida [inn-spanish] Liraglutidec g34 GLP-1-OH High Purity Liraglutide inhibit,Liraglutide,Glucagon Rector,Inhibitor Liraglutide, NN2211 LiraglutideQ: What is Liraglutide Q: What is the CAS Number of Liraglutide Q: What is the storage condition of Liraglutide Q: What e the applications of Liraglutide H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(g-Glu-palMitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-g-Gly-g-Gly-OH N26-(Hexadecanoyl-gamma-glutamyle)-(34-ginine)glp-1-ptide Lose Weight Ptides Liraglutide Liraglutide Impurity HAEGTFTSDVSSYLEGQAAK [N-(1-oxohexadecyl)-L-γ-glutaMyl] EFI AWLVRG N26-(Hexadecanoyl-gamma-glutamyle)-(34-ginine)glucagon-like-ptide-1-ptide Liraglutida (Lys(γ-Glu-palMitoyl)26,g34)-GLP-1 Liraglutide, NN2211 Liroglutide The lalu ptide Glycine, L-histidyl-L-alanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-asptyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-(N-(1-oxohexadecyl)-L-gamma-glutamyl)-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-ginylglycyl-L-ginyl Liraglutide (sodium salt) NNC 0 Liraglutide D4Q: What is Liraglutide D4 Q: What is the CAS Number of Liraglutide D4 Q: What is the storage condition of Liraglutide D4 Q: What e the applications of Liraglutide D4 Victoza (Lys(g-Glu-palMitoyl)26,g34)-GLP-1 |
| Description | Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus. |
|---|---|
| Related Catalog | |
| Target |
GLP-1 receptor[1] |
| In Vitro | Liraglutide binds to the same receptors as does the endogenous metabolic hormone GLP-1 that stimulates insulin secretion. Liraglutide is an injectable drug for the treatment of type 2 diabetes, also can be used to treat obesity in adults with some related comorbidity. Liraglutide activated AMPK/SREBP1 pathway in oxLDL-stimulated Raw264.7 cells[1]. |
| Cell Assay | Raw264.7 macrophage cells are cultured in Dulbecco's modified Eagle's medium supplemented with 10% fetal bovine serum in a humidified 37°C incubator with 5% CO2. The cells are incubated with oxLDL (50 μg/mL), Liraglutide (0.1, 0.5, 1 and 2 nM) or Exendin-3 (9-39) (1, 10 and 100 nM) alone, or in combination[1]. |
| References |
| Molecular Formula | C172H265N43O51 |
|---|---|
| Molecular Weight | 3751.20000 |
| Exact Mass | 3748.95000 |
| PSA | 1513.76000 |
| LogP | 6.12960 |
| Storage condition | -20°C |