N-Boc-N-bis(PEG4-azide)

Modify Date: 2024-01-09 11:46:47

N-Boc-N-bis(PEG4-azide) Structure
N-Boc-N-bis(PEG4-azide) structure
Common Name N-Boc-N-bis(PEG4-azide)
CAS Number 2055041-25-1 Molecular Weight 607.70
Density N/A Boiling Point N/A
Molecular Formula C25H49N7O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Boc-N-bis(PEG4-azide)


N-Boc-N-bis(PEG4-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-Boc-N-bis(PEG4-azide)

 N-Boc-N-bis(PEG4-azide) Biological Activity

Description N-Boc-N-bis(PEG4-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C25H49N7O10
Molecular Weight 607.70