Biotin-PEG3-Bis-sulfone

Modify Date: 2024-01-09 22:23:31

Biotin-PEG3-Bis-sulfone Structure
Biotin-PEG3-Bis-sulfone structure
Common Name Biotin-PEG3-Bis-sulfone
CAS Number 2055048-58-1 Molecular Weight 901.12
Density N/A Boiling Point N/A
Molecular Formula C43H56N4O11S3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG3-Bis-sulfone


Biotin-PEG3-Bis-sulfone is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG3-Bis-sulfone

 Biotin-PEG3-Bis-sulfone Biological Activity

Description Biotin-PEG3-Bis-sulfone is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.

 Chemical & Physical Properties

Molecular Formula C43H56N4O11S3
Molecular Weight 901.12