Benzylhydrazine dihydrochloride

Modify Date: 2024-01-03 17:15:39

Benzylhydrazine dihydrochloride Structure
Benzylhydrazine dihydrochloride structure
Common Name Benzylhydrazine dihydrochloride
CAS Number 20570-96-1 Molecular Weight 195.090
Density 1.033g/cm3 Boiling Point 265.4ºC at 760 mmHg
Molecular Formula C7H12Cl2N2 Melting Point 143-145 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 132ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Benzylhydrazine dihydrochloride




 Names

Name benzylhydrazine,dihydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.033g/cm3
Boiling Point 265.4ºC at 760 mmHg
Melting Point 143-145 °C (dec.)(lit.)
Molecular Formula C7H12Cl2N2
Molecular Weight 195.090
Flash Point 132ºC
Exact Mass 194.037750
PSA 38.05000
LogP 3.34510

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MU8540000
CHEMICAL NAME :
Hydrazine, benzyl-, dihydrochloride
CAS REGISTRY NUMBER :
20570-96-1
LAST UPDATED :
198910
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C7-H10-N2.2Cl-H
MOLECULAR WEIGHT :
195.11
WISWESSER LINE NOTATION :
ZM1R &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
11 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Behavioral - antipsychotic
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
10 gm/kg/29W-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - lymphoma, including Hodgkin's disease

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Bacteria - Bacillus subtilis
DOSE/DURATION :
10 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 5,343,1968

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS MU8540000
Hazard Class 6.1
HS Code 2928000090

 Synthetic Route

~%

Benzylhydrazine dihydrochloride Structure

Benzylhydrazine...

CAS#:20570-96-1

Literature: Synlett, , # 13 p. 2355 - 2356

 Preparation


 Customs

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Articles8

More Articles
Determination of hydrazine in pharmaceuticals IV: Hydrazine and benzylhydrazine in isocarboxazid.

J. Pharm. Sci. 74(1) , 105-7, (1985)

A GC procedure for the simultaneous determination of hydrazine and benzylhydrazine in isocarboxazid raw material and tablet formulations has been developed. The method is based on the reaction of benz...

Benzylhydrazine as a pseudo-substrate of bovine serum amine oxidase.

Biochem. J. 260(1) , 19-25, (1989)

Bovine serum amine oxidase is inhibited by benzylhydrazine (BHy), but recovers full activity after a few hours incubation [Hucko-Haas & Reed (1970) Biochem. Biophys. Res. Commun. 38, 396-400]. The fir...

Discovery and SAR of indole-2-carboxylic acid benzylidene-hydrazides as a new series of potent apoptosis inducers using a cell-based HTS assay.

Bioorg. Med. Chem. 12(13) , 3649-55, (2004)

A series of indole-2-carboxylic acid benzylidene-hydrazides has been identified as a new class of potent apoptosis inducers through a novel cell-based caspase HTS assay. The screening hit, 5-chloro-3-...

 Synonyms

EINECS 243-887-1
BENZYL HYDRAZINE di HCl
Benzylhydrazine dihydrochloride
1-benzylhydrazine dihydrochloride
Hydrazine,benzyl-,dihydrochloride
Hydrazine, (phenylmethyl)-, hydrochloride (1:2)
BnNHNH2*2HCl
N-benzylhydrazine dihydrochloride
(phenylmethyl)hydrazine dihydrochloride
benzylhydrazine*2HCl
MFCD00012921
Benzyl-hydrazine dihydrochloride
benzylhydrazine dihydrogen chloride