BB-78485
Modify Date: 2025-08-25 16:24:46
BB-78485 structure
|
Common Name | BB-78485 | ||
|---|---|---|---|---|
| CAS Number | 207732-11-4 | Molecular Weight | 420.48 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C23H20N2O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BB-78485BB-78485 is an LpxC metalloenzyme inhibitor with antibacterial activity. BB-78485 can inhibit LpxC with an IC50 value of 160 nM. BB-78485 can be used for the research of gram-negative selective antibacterials[1]. |
| Name | N-Hydroxy-3-(2-naphthyl)-N2-(2-naphthylsulfonyl)-D-alaninamide |
|---|---|
| Synonym | More Synonyms |
| Description | BB-78485 is an LpxC metalloenzyme inhibitor with antibacterial activity. BB-78485 can inhibit LpxC with an IC50 value of 160 nM. BB-78485 can be used for the research of gram-negative selective antibacterials[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 160 nM(LpxC)[1] |
| In Vitro | BB-78485 可以抑制 LpxC，IC50 值为 160 nM[1]。 BB-78485 对 D21 和 D22 (lpxC101) 有作用，MIC 值分别为 2 μg/mL 和 0.016 μg/mL[1]。 BB-78485 对Enterobacteriaceae, Serratia marcescens, Morganella morganii, Moraxella catarrhalis, Haemophilus influenzae和 Burkholderia cepacia的 MIC 值范围为 1μg/mL 至 32μg/mL[1]。 |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C23H20N2O4S |
| Molecular Weight | 420.48 |
| Exact Mass | 420.114380 |
| LogP | 4.05 |
| Index of Refraction | 1.700 |
| (2R)-N-hydroxy-3-naphthalen-2-yl-2-[(naphthalen-2-ylsulfonyl)amino]propanamide |
| N-Hydroxy-3-(2-naphthyl)-N2-(2-naphthylsulfonyl)-D-alaninamide |
| 2-Naphthalenepropanamide, N-hydroxy-α-[(2-naphthalenylsulfonyl)amino]-, (αR)- |
| BB-78485 |