Isobavachalcone

Modify Date: 2024-01-03 04:31:14

Isobavachalcone structure	Common Name	Isobavachalcone
	CAS Number	20784-50-3	Molecular Weight	324.370
	Density	1.2±0.1 g/cm3	Boiling Point	549.0±50.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₀O₄	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	299.9±26.6 °C

Use of Isobavachalcone

Isobavachalcone(Corylifolinin) is a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma.IC50 value:Target: Isobavachalcone inhibits platelet aggregation. Inhibitor of Epstein-Barr virus early antigen (EBV-EA) induction. Isobavachalcone exhibits potent inhibitory effect on skin tumor promotion. Potent inhibitor of MMP-2. Displays DNA strand-scission (cleaving) activity. Isobavachalcone hows antifungal activity.

Name	Isobavachalcone
Synonym	More Synonyms

Description	Isobavachalcone(Corylifolinin) is a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma.IC50 value:Target: Isobavachalcone inhibits platelet aggregation. Inhibitor of Epstein-Barr virus early antigen (EBV-EA) induction. Isobavachalcone exhibits potent inhibitory effect on skin tumor promotion. Potent inhibitor of MMP-2. Displays DNA strand-scission (cleaving) activity. Isobavachalcone hows antifungal activity.
Related Catalog	Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Cancer Natural Products >> Flavonoids
References	[1]. Jing Hui; Zhou Xinglu; Dong Xiaowu; Cao Ji; Zhu Hong; Lou Jianshu; Hu Yongzhou; He Qiaojun; Yang Bo Abrogation of Akt signaling by Isobavachalcone contributes to its anti-proliferative effects towards human cancer cells.Cancer letters (2010), 294(2):167-177 [2]. Nishimura R et al. Isobavachalcone, a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma. Biol Pharm Bull. 2007 Oct;30(10):1878-83. [3]. Zhao S, et al. Autophagy inhibition enhances isobavachalcone-induced cell death in multiple myeloma cells.Int J Mol Med. 2012 Jul 16. [4]. Kuete V, Sandjo LP.Isobavachalcone: an overview.Chin J Integr Med. 2012 Jul;18(7):543-7. Epub 2012 Jul 7. [5]. Zhang Y, Chen Z.Separation of isomeric bavachin and isobavachalcone in the fructus Psoraleae by capillary electrophoresis-mass spectrometry.J Sep Sci. 2012 Jul;35(13):1644-50.

Description

Related Catalog

Signaling Pathways >> Autophagy >> Autophagy

Research Areas >> Cancer

Natural Products >> Flavonoids

References

[1]. Jing Hui; Zhou Xinglu; Dong Xiaowu; Cao Ji; Zhu Hong; Lou Jianshu; Hu Yongzhou; He Qiaojun; Yang Bo Abrogation of Akt signaling by Isobavachalcone contributes to its anti-proliferative effects towards human cancer cells.Cancer letters (2010), 294(2):167-177

[2]. Nishimura R et al. Isobavachalcone, a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma. Biol Pharm Bull. 2007 Oct;30(10):1878-83.

[3]. Zhao S, et al. Autophagy inhibition enhances isobavachalcone-induced cell death in multiple myeloma cells.Int J Mol Med. 2012 Jul 16.

[4]. Kuete V, Sandjo LP.Isobavachalcone: an overview.Chin J Integr Med. 2012 Jul;18(7):543-7. Epub 2012 Jul 7.

[5]. Zhang Y, Chen Z.Separation of isomeric bavachin and isobavachalcone in the fructus Psoraleae by capillary electrophoresis-mass spectrometry.J Sep Sci. 2012 Jul;35(13):1644-50.

Density	1.2±0.1 g/cm3
Boiling Point	549.0±50.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₀O₄
Molecular Weight	324.370
Flash Point	299.9±26.6 °C
Exact Mass	324.136169
PSA	77.76000
LogP	5.21
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.658

Hazard Codes	Xi
RIDADR	NONH for all modes of transport

(2E)-1-[2,4-Dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one

4-Hydroxyisocordoim

2',4',4-trihydroxy-3'-prenylchalcone

4-Hydroxyisocordoin

Isobacachalcone

4,2',4'-trihydroxy-3'-prenylchalcone

(E)-1-[2,4-dihydroxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one

2-Propen-1-one, 1-[2,4-dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-, (2E)-

Corylifolinin

BioBioPha
China
Product Name: Isobavachalcone
Price: ￥Inquiry/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Isobavachalcone
Price: ￥588.0/20mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Corylifolinin(Isobavachalcone)
Price: $550.0/100mg $950.0/250mg $1700.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Isobavachalcone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: ISOBAVACHALCONE
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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Price: $92/10mM*1mLinDMSO

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Isobavachalcone

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