TP-472
Modify Date: 2024-01-23 19:16:12
TP-472 structure
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Common Name | TP-472 | ||
|---|---|---|---|---|
| CAS Number | 2079895-62-6 | Molecular Weight | 333.384 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C20H19N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TP-472TP-472 is a novel BRD9/7 chemical probe that has excellent potency (BRD9 KD=33nM; BRD7 KD=340 nM by ITC), >30 fold selectivity over all other bromodomain family members except BRD7 and is cell active (EC50 320 nM in a BRD9 NanoBRET assay); has a good PK profile and is suitable for in vivo applications. |
| Name | TP-472 |
|---|---|
| Synonym | More Synonyms |
| Description | TP-472 is a novel BRD9/7 chemical probe that has excellent potency (BRD9 KD=33nM; BRD7 KD=340 nM by ITC), >30 fold selectivity over all other bromodomain family members except BRD7 and is cell active (EC50 320 nM in a BRD9 NanoBRET assay); has a good PK profile and is suitable for in vivo applications. |
|---|---|
| References | References 1. Pérez-Salvia M, et al. Epigenetics. 2017 May 4;12(5):323-339. View Related Products by Target Bromodomain |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C20H19N3O2 |
| Molecular Weight | 333.384 |
| Exact Mass | 333.147736 |
| LogP | 1.25 |
| Index of Refraction | 1.681 |
| 3-(6-Acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methylbenzamide |
| 3-(6-Acetyl-pyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methyl-benzamide |
| TP-472 |
| MFCD30536375 |
| Benzamide, 3-(6-acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methyl- |