NS5A-IN-4

Modify Date: 2024-01-14 15:33:06

NS5A-IN-4 Structure
NS5A-IN-4 structure
Common Name NS5A-IN-4
CAS Number 2088243-03-0 Molecular Weight 820.93
Density N/A Boiling Point N/A
Molecular Formula C47H48N8O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NS5A-IN-4


NS5A-IN-4 (Compound 1.12) is an orally active pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with IC50 values of 1.2, 2296, 4.6, 362, 10.3 and 693 pM against gT1b, gT1a, gT2a, gT3a, gT4a and gT5a[1].

 Names

Name NS5A-IN-4

 NS5A-IN-4 Biological Activity

Description NS5A-IN-4 (Compound 1.12) is an orally active pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with IC50 values of 1.2, 2296, 4.6, 362, 10.3 and 693 pM against gT1b, gT1a, gT2a, gT3a, gT4a and gT5a[1].
Related Catalog
Target

IC50: 1.2 pM (gT1b), 4.6 pM (gT2a), 10.3 pM (gT4a), 362 pM (gT3a), 693 pM (gT5a), 2296 pM (gT1a)[1]

References

[1]. Ivashchenko AA, et al. Synthesis, biological evaluation and in silico modeling of novel pan-genotypic NS5A inhibitors. Bioorg Med Chem. 2020 Oct 15;28(20):115716.

 Chemical & Physical Properties

Molecular Formula C47H48N8O6
Molecular Weight 820.93