NAcM-COV

Modify Date: 2024-01-30 19:16:40

NAcM-COV Structure
NAcM-COV structure
Common Name NAcM-COV
CAS Number 2089293-81-0 Molecular Weight 516.609
Density N/A Boiling Point N/A
Molecular Formula C28H35F3N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NAcM-COV


NAcM-COV is a specific, irreversible small molecule inhibitor targeting N-Acetyl-UBE2M interaction with DCN1 with IC50 of 28 nM in TR-FRET assays; shows highly selectivity with respect to other protein acetyl-amide-binding sites; inhibits NEDD8 ligation in vitro and in cells, and suppress anchorage-independent growth of a cell line with DCN1 amplification.

 Names

Name NAcM-COV

 NAcM-COV Biological Activity

Description NAcM-COV is a specific, irreversible small molecule inhibitor targeting N-Acetyl-UBE2M interaction with DCN1 with IC50 of 28 nM in TR-FRET assays; shows highly selectivity with respect to other protein acetyl-amide-binding sites; inhibits NEDD8 ligation in vitro and in cells, and suppress anchorage-independent growth of a cell line with DCN1 amplification.
References References 1. Scott DC, et al. Nat Chem Biol. 2017 Aug;13(8):850-857. View Related Products by Target Ubiquitin-conjugating Enzyme (E2)

 Chemical & Physical Properties

Molecular Formula C28H35F3N4O2
Molecular Weight 516.609
Top Suppliers:I want be here



Get all suppliers and price by the below link:

NAcM-COV suppliers

NAcM-COV price