SARS-CoV-2 nsp3-IN-2

Modify Date: 2024-01-12 07:10:35

SARS-CoV-2 nsp3-IN-2 Structure
SARS-CoV-2 nsp3-IN-2 structure
Common Name SARS-CoV-2 nsp3-IN-2
CAS Number 2038858-11-4 Molecular Weight 220.23
Density N/A Boiling Point N/A
Molecular Formula C10H12N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SARS-CoV-2 nsp3-IN-2


SARS-CoV-2 nsp3-IN-2 is a macrodomain (Mac1) inhibitor with IC50 value of 180 μM. SARS-CoV-2 nsp3-IN-2 is a small molecule chemical probe and can be used for the research of viral[1].

 Names

Name SARS-CoV-2 nsp3-IN-2

 SARS-CoV-2 nsp3-IN-2 Biological Activity

Description SARS-CoV-2 nsp3-IN-2 is a macrodomain (Mac1) inhibitor with IC50 value of 180 μM. SARS-CoV-2 nsp3-IN-2 is a small molecule chemical probe and can be used for the research of viral[1].
Related Catalog
Target

IC50: 180 μM (Mac1)[1]

In Vitro SARS-CoV-2 nsp3-IN-2 emonstrates weak potency against Mac1 in an ADP-ribose binding AlphaScreen assay with IC50 value of 180 μM[1].
References

[1]. Lavinia M Sherrill, et al. Design, Synthesis and Evaluation of Inhibitors of the SARS-CoV2 nsp3 Macrodomain. bioRxiv. 2022 Feb 28;2022.02.27.482176.

 Chemical & Physical Properties

Molecular Formula C10H12N4O2
Molecular Weight 220.23
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