SARS-CoV-2-IN-35

Modify Date: 2024-01-16 19:35:10

SARS-CoV-2-IN-35 structure	Common Name	SARS-CoV-2-IN-35
	CAS Number	2757763-47-4	Molecular Weight	621.67
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₃₄F₃N₅O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SARS-CoV-2-IN-35

SARS-CoV-2-IN-35 is a potent and orally active SARS-CoV-2 M pro inhibitor with a Ki value of 12.1 nM. SARS-CoV-2-IN-35 can be used in research of COVID-19[1].

Name	SARS-CoV-2-IN-35

Description	SARS-CoV-2-IN-35 is a potent and orally active SARS-CoV-2 M pro inhibitor with a Ki value of 12.1 nM. SARS-CoV-2-IN-35 can be used in research of COVID-19[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
In Vivo	SARS-CoV-2-IN-35 (compound 5; 10 mg/kg; p.o.) has good oral utilization in Wistar-Han rats[1]. Animal Model: Wistar-Han rats[1] Dosage: 10 mg/kg Administration: Oral administration Result: Had oral F of 33 %.
References	[1]. Owen DR, et, al. An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19. Science. 2021 Dec 24;374(6575):1586-1593.

Molecular Formula	C₂₉H₃₄F₃N₅O₅S
Molecular Weight	621.67